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2009 年对 344 例未经选择的连续糖尿病患者进行评估的结果显示,糖尿病合并严重肢体缺血患者肢体血运重建的可行性。

Limb revascularization feasibility in diabetic patients with critical limb ischemia: results from a cohort of 344 consecutive unselected diabetic patients evaluated in 2009.

机构信息

Diabetology Centre, Diabetic Foot Centre, IRCCS Multimedica, Via Milanese 300, 20099 Sesto San Giovanni, Milano, Italy.

出版信息

Diabetes Res Clin Pract. 2012 Mar;95(3):364-71. doi: 10.1016/j.diabres.2011.10.033. Epub 2011 Nov 21.

Abstract

AIMS

To evaluate the feasibility of peripheral revascularization by angioplasty (PTA) or bypass grafting (BPG) in diabetic patients with critical limb ischemia (CLI).

METHODS

All diabetic patients referred to our Diabetic Foot Centre for foot lesion or rest pain were assessed for the presence of CLI as assessed by the TASC criteria. All patients underwent angiography that was evaluated jointly by an interventional radiologist, a vascular surgeon and a diabetologist of the diabetic foot care team.

RESULTS

During 2009, 344 diabetics were admitted because of CLI in a total of 360 limbs. PTA was performed in 308 (85.6%) limbs, and BPG was performed in 40 (11.1%) limbs in which PTA was not feasible. Revascularization could not be carried out in 12 (3.3%) limbs due to the lack of target vessel (9 limbs) or high surgical risk (3 limbs). According to the judgement of the vascular surgeon, BPG was anatomically feasible in 180 (58.4%) of the 308 limbs that underwent PTA. Therefore, considering also the 40 limbs that underwent BPG, surgical revascularization was judged anatomically possible in a total of 220 (61.1%) limbs. At 30 days, 19 (5.3%) above-the-ankle amputations were performed: 8 (66.7%) amputations were performed in the 12 non-revascularized limbs, 8 (2.6%) amputations were performed in the 308 limbs treated with PTA and 3 (7.5%) amputations were performed in the 40 limbs treated with BPG.

CONCLUSIONS

Revascularization by PTA is highly feasible in diabetics with CLI. The feasibility of revascularization by BPG is lower but nonetheless consistent. In centres where both revascularization procedures are available, it is possible to revascularize more than 96% of diabetics with CLI.

摘要

目的

评估经皮血管成形术(PTA)或旁路移植术(BPG)在外周血管病变治疗糖尿病合并严重肢体缺血(CLI)患者中的可行性。

方法

所有因足部病变或静息痛就诊于我院糖尿病足中心的糖尿病患者,均按照 TASC 标准评估 CLI 的存在。所有患者均接受血管造影检查,由介入放射科医生、血管外科医生和糖尿病足护理团队的糖尿病专家共同评估。

结果

2009 年,共有 344 例糖尿病患者因 CLI 入住我院,共涉及 360 条肢体。308 条肢体(85.6%)接受了 PTA,40 条肢体(11.1%)因 PTA 不可行而接受了 BPG。12 条肢体(3.3%)因缺乏靶血管(9 条肢体)或高手术风险(3 条肢体)而无法进行血运重建。根据血管外科医生的判断,在接受 PTA 的 308 条肢体中,180 条(58.4%)解剖上可行 BPG。因此,考虑到接受 BPG 的 40 条肢体,总共 220 条(61.1%)肢体解剖上可行手术血运重建。术后 30 天,有 19 例(5.3%)踝关节以上截肢:12 条未血运重建的肢体中有 8 例(66.7%)截肢,308 条接受 PTA 治疗的肢体中有 8 例(2.6%)截肢,40 条接受 BPG 治疗的肢体中有 3 例(7.5%)截肢。

结论

PTA 治疗糖尿病合并 CLI 的血运重建具有较高的可行性。BPG 血运重建的可行性较低,但仍然一致。在同时开展这两种血管重建术的中心,96%以上的糖尿病合并 CLI 患者可以获得血运重建。

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