Aneeza W H, Marina M B, Razif M Y, Azimatun N A, Asma A, Sani A
Department of Otorhinolaryngology and Head & Neck Surgery, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.
Med J Malaysia. 2011 Jun;66(2):129-32.
To review the long term outcome of Uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnoea syndrome in a tertiary referral centre. 38 records were traced where UPPP was done from July 2000 to December 2007. 14 patients were followed up for one to seven years where the Epworth sleepiness scale was scored, long term side effects documented and post operative muller's manoeuvre done. Success of UPPP is defined as a reduction in apnoea hypopnea index (AHI) more than 50%. Sixty percent (60%) were successfully treated with UPPP in the long term. Mean ESS was significantly reduced from 12 +/- 6 to 7 +/- 4. 11 out of 14 patients (78.5%) were reported to develop long term side effects of UPPP, the highest being velopharyngeal insufficiency (42.8%). In conclusion, UPPP is effective in improving symptoms of OSA in the long term. However, in view of its side effects, uvula preserving surgery should be considered as a surgical option.
回顾一家三级转诊中心悬雍垂腭咽成形术(UPPP)治疗阻塞性睡眠呼吸暂停综合征的长期疗效。追踪了2000年7月至2007年12月期间进行UPPP手术的38份病例记录。14名患者接受了1至7年的随访,期间进行了Epworth嗜睡量表评分、记录长期副作用并进行了术后米勒动作。UPPP手术成功的定义为呼吸暂停低通气指数(AHI)降低超过50%。从长期来看,60%的患者通过UPPP手术得到成功治疗。平均Epworth嗜睡量表评分从12±6显著降至7±4。据报告,14名患者中有11名(78.5%)出现了UPPP手术的长期副作用,其中最常见的是腭咽闭合不全(42.8%)。总之,UPPP手术从长期来看能有效改善阻塞性睡眠呼吸暂停(OSA)的症状。然而,鉴于其副作用,保留悬雍垂的手术应被视为一种手术选择。