Department of Neurological Surgery, Northwestern University Feinberg School of Medicine and McGaw Medical Center, 676 North Saint Clair Street, Chicago, IL 60611, USA.
Neurosurg Clin N Am. 2012 Jan;23(1):87-103. doi: 10.1016/j.nec.2011.09.013.
Arteriovenous malformations of the brain (AVMs) are a major cause of stroke in young, healthy individuals and present multiple diagnostic and therapeutic challenges, particularly in the acute setting. Although the flow hemodynamics, biology, epidemiology, and natural history of AVMs have been extensively studied, little data have been published on AVM surgery in the acute setting, and acute surgery has been claimed to possibly increase the risk of persistent neurological deficits. Although it is usually preferable to defer AVM surgery for a few weeks or months, acute surgical (open and endovascular) management is essential in specific clinical and radiological settings.
脑动静脉畸形(AVM)是年轻健康个体中风的主要原因,存在多种诊断和治疗挑战,尤其是在急性发病期。尽管 AVM 的血流动力学、生物学、流行病学和自然病史已经得到了广泛的研究,但在急性发病期的 AVM 手术方面发表的数据很少,而且有人声称急性手术可能会增加持续性神经功能缺损的风险。尽管通常最好将 AVM 手术推迟数周或数月,但在特定的临床和影像学环境下,急性手术(开放手术和血管内治疗)是必要的。