Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
World Neurosurg. 2012 Feb;77(2):362-9. doi: 10.1016/j.wneu.2011.06.062. Epub 2011 Nov 7.
To determine the effectiveness of C2 nerve root decompression and C2 dorsal root ganglionectomy for intractable occipital neuralgia (ON) and C2 ganglionectomy after pain recurrence following initial decompression.
A retrospective review was performed of the medical records of patients undergoing surgery for ON. Pain relief at the time of the most recent follow-up was rated as excellent (headache relieved), good (headache improved), or poor (headache unchanged or worse). Telephone contact supplemented chart review, and patients rated their preoperative and postoperative pain on a 10-point numeric scale. Patient satisfaction and disability were also examined.
Of 43 patients, 29 were available for follow-up after C2 nerve root decompression (n = 11), C2 dorsal root ganglionectomy (n = 10), or decompression followed by ganglionectomy (n = 8). Overall, 19 of 29 patients (66%) experienced a good or excellent outcome at most recent follow-up. Among the 19 patients who completed the telephone questionnaire (mean follow-up 5.6 years), patients undergoing decompression, ganglionectomy, or decompression followed by ganglionectomy experienced similar outcomes, with mean pain reduction ratings of 5 ± 4.0, 4.5 ± 4.1, and 5.7 ± 3.5. Of 19 telephone responders, 13 (68%) rated overall operative results as very good or satisfactory.
In the third largest series of surgical intervention for ON, most patients experienced favorable postoperative pain relief. For patients with pain recurrence after C2 decompression, salvage C2 ganglionectomy is a viable surgical option and should be offered with the potential for complete pain relief and improved quality of life (QOL).
确定 C2 神经根减压和 C2 背根神经节切除术治疗难治性枕神经痛(ON)的疗效,以及初次减压后疼痛复发时行 C2 神经节切除术的疗效。
对接受手术治疗 ON 的患者的病历进行回顾性研究。最近一次随访时的疼痛缓解情况评定为优(头痛缓解)、良(头痛改善)或差(头痛无变化或加重)。通过电话联系补充图表审查,患者对术前和术后的疼痛进行 10 分制评分。还检查了患者的满意度和残疾情况。
43 例患者中,29 例在 C2 神经根减压(n=11)、C2 背根神经节切除术(n=10)或减压后继行神经节切除术(n=8)后获得了随访。总体而言,29 例患者中有 19 例(66%)在最近一次随访时获得了良好或优的结果。在完成电话问卷调查的 19 例患者中(平均随访 5.6 年),接受减压、神经节切除术或减压后继行神经节切除术的患者的结局相似,平均疼痛缓解评分分别为 5±4.0、4.5±4.1 和 5.7±3.5。在 19 例电话应答者中,13 例(68%)总体手术结果评为非常好或满意。
在第三大系列的 ON 手术干预中,大多数患者术后疼痛缓解情况良好。对于 C2 减压后疼痛复发的患者,挽救性 C2 神经节切除术是一种可行的手术选择,可提供完全缓解疼痛和改善生活质量(QOL)的潜力。