阿尔茨海默病中的记忆再巩固训练和转移效应：重复滞后程序的有效性。
Recollection training and transfer effects in Alzheimer's disease: effectiveness of the repetition-lag procedure.
机构信息
Laboratoire de Psychologie et Neuropsychologie Cognitives, Institut de Psychologie, Université Paris Descartes, Paris, France.
出版信息
Brain Cogn. 2012 Mar;78(2):169-77. doi: 10.1016/j.bandc.2011.10.011. Epub 2011 Nov 26.
OBJECTIVE
This study was designed to extend the use of a memory training technique, known as the repetition-lag procedure, to Alzheimer patients. The specificity of this procedure is to target the process of recollection for improvement.
METHOD
A group of 12 patients were trained individually for 6h. The training procedure consisted of a series of yes/no recognition tasks in which some words were repeated throughout the test list across gradually increasing delays. Their performance was evaluated on pre-and-post tests and compared with a recognition practice group and a no contact control group.
RESULTS
Initially, recollection training patients only performed accurately when the delay between repetitions consisted of one intervening word, but by the end of training their performance increased up to four-word intervals. Interestingly, these benefits generalized to other measures of memory, such as working memory, visual memory and source recognition.
CONCLUSIONS
Effectiveness of the repetition-lag procedure in Alzheimer's disease is discussed.
目的
本研究旨在将一种记忆训练技术（称为重复滞后程序）扩展应用于阿尔茨海默病患者。该程序的特异性在于针对回忆过程进行改善。
方法
将 12 名患者分为一组，进行单独训练 6 小时。训练程序由一系列是/否识别任务组成，其中一些单词在整个测试列表中重复出现，延迟逐渐增加。在预测试和后测试中评估他们的表现，并与识别练习组和无接触对照组进行比较。
结果
最初，回忆训练患者仅在重复之间的延迟包含一个插入词时才能准确表现，但在训练结束时，他们的表现提高到了四个词的间隔。有趣的是，这些益处推广到了其他记忆测量，如工作记忆、视觉记忆和来源识别。
结论
讨论了重复滞后程序在阿尔茨海默病中的有效性。
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