School of Experimental Psychology, University of Bristol, Bristol, UK.
Int J Obes (Lond). 2012 Sep;36(9):1222-8. doi: 10.1038/ijo.2011.237. Epub 2011 Nov 29.
BACKGROUND/OBJECTIVES: Fabuless (Olibra) is a commercially structured lipid emulsion, claimed to be a food ingredient that is effective for food intake and appetite reduction. The present study assessed its efficacy in a yoghurt-based mini-drink undergoing low or minimal food manufacturing (thermal and shear) processes.
SUBJECTS/METHODS: Study 1: Twenty-four healthy volunteers (16 female, 8 male; age: 18-47 years; body mass index (BMI): 17-28 kg m(-2)) took part in a randomised, placebo-controlled, double-blind parallel crossover trial. Consumption of a minimally processed 'preload' mini-drink (containing two different doses of Fabuless or a control fat) at 2 h after breakfast was followed by appetite and mood ratings, and food intake measured in ad libitum meals at 3 and 7 h post consumption of the preload. Study 2: As Study 1 (16 female, 8 male; age: 20-54 years; BMI: 21-30 kg m(-2)). A chilled, virtually unprocessed, preload breakfast mini-drink (containing minimally processed Fabuless or a control fat) was provided 5 min after a standardised breakfast, followed by appetite and mood ratings, and food intake measured in ad libitum meals at 4 and 8 h post consumption of the preload.
The structured lipid emulsion tested had no significant effect on the primary measures of food intake or appetite.
Even when exposed to minimal food-manufacturing conditions, Fabuless showed no efficacy on measures of appetite and food intake.
背景/目的:Fabuless(Olibra)是一种商业化的结构脂质乳液,据称是一种有效的食品成分,可促进食物摄入和减少食欲。本研究评估了其在经过低或最小食品加工(热和剪切)过程的酸奶基迷你饮料中的功效。
受试者/方法:研究 1:24 名健康志愿者(16 名女性,8 名男性;年龄:18-47 岁;体重指数(BMI):17-28kg/m²)参加了一项随机、安慰剂对照、双盲平行交叉试验。在早餐后 2 小时内饮用一种经过最小加工的“预食”迷你饮料(含有两种不同剂量的 Fabuless 或对照脂肪),然后在预食后 3 和 7 小时进行食欲和情绪评分,并进行自由进食餐的食物摄入量测量。研究 2:与研究 1 相同(16 名女性,8 名男性;年龄:20-54 岁;BMI:21-30kg/m²)。在标准早餐后 5 分钟提供一种冷藏的、几乎未经加工的预食早餐迷你饮料(含有经过最小加工的 Fabuless 或对照脂肪),然后进行食欲和情绪评分,并在预食后 4 和 8 小时进行自由进食餐的食物摄入量测量。
测试的结构化脂质乳液对食物摄入量或食欲的主要测量指标没有显著影响。
即使暴露于最小的食品加工条件下,Fabuless 对食欲和食物摄入量的测量也没有效果。