Nair Arun B, Chaturvedi Jagdish, Venkatasubbareddy Manjula Battlahalli, Correa Majorie, Rajan Nandakumar, Sawkar Anisha
Department of Otorhinolaryngology-Head and Neck Surgery, St John's Medical College, Bangalore 560 029, India.
Malays J Med Sci. 2011 Jul;18(3):75-8.
Respiratory fungal infections are usually found in immunocompromised individuals who have received either long-term steroid therapy or broad-spectrum anti-microbial therapy or have a non-resolving underlying chronic disease. These infections are seen as a part of bronchopulmonary fungal infections, and their isolated and primary occurrence as laryngeal diseases is highly uncommon. Laryngeal fungal infections can also mimic various diseases, such as gastroesophageal reflux disease, granulomatous diseases, leukoplakia, and carcinoma, thereby misleading the treating team from correct diagnosis and management. It is therefore important to identify the lesion at the earliest point possible to avoid morbid or life-threatening consequences. We report a case of isolated laryngeal candidiasis in an immunocompetent Indian male with an unusual presentation mimicking laryngeal carcinoma. The clinical and histological features are highlighted with a review of relevant literature to demonstrate the possibility of such an isolated fungal lesion, even in an immunocompetent individual.
呼吸道真菌感染通常见于免疫功能低下的个体,这些个体接受过长期类固醇治疗或广谱抗菌治疗,或患有无法治愈的潜在慢性疾病。这些感染被视为支气管肺真菌感染的一部分,而其作为喉部疾病单独发生且为原发性的情况极为罕见。喉部真菌感染也可模仿多种疾病,如胃食管反流病、肉芽肿性疾病、白斑病和癌,从而误导治疗团队进行正确的诊断和管理。因此,尽早识别病变以避免出现病态或危及生命的后果非常重要。我们报告一例免疫功能正常的印度男性孤立性喉部念珠菌病病例,其表现不寻常,类似喉癌。通过回顾相关文献突出了临床和组织学特征,以证明即使在免疫功能正常的个体中也可能出现这种孤立性真菌病变。