Suppr超能文献

[精神病与创伤。创伤后症状与精神病症状之间的理论联系]

[Psychosis and trauma. Theorical links between post-traumatic and psychotic symptoms].

作者信息

Auxéméry Y, Fidelle G

机构信息

Service de psychiatrie et de psychologie clinique, hôpital d'instruction des armées Legouest, Metz, France.

出版信息

Encephale. 2011 Dec;37(6):433-8. doi: 10.1016/j.encep.2010.12.001. Epub 2011 Feb 2.

Abstract

INTRODUCTION

The co-occurrence between post-traumatic symptoms and psychotic symptoms is well described in the immediate suites of a trauma but can also be chronic. This symptomatic co-occurrence, rarely studied in the literature, is often approached under the sole angle of a primary post-traumatic stress disorder (PTSD) or of a primary psychosis, without federative will to unify the psychotic and post-traumatic symptoms within the same nosological framework. Individuals with schizophrenia or schizoaffective disorder report higher rates of trauma and assault than the general population.

LITERATURE FINDINGS

High rates of PTSD have been noted in severe mental illness cohorts. Psychotic phenomena may be a relatively common manifestation in patients with chronic PTSD.

AIM

The purpose of this paper is to expose the various theorical psychopathological aspects between the symptoms of psychosis and PTSD. In populations of veterans, positive and negative symptoms of psychosis in PTSD are described as delusional thoughts and hallucinations often combat-specific.

CLINICAL FINDINGS

When a PTSD becomes established at a subject to the personality of neurotic structure, the intensity of the PTSD's symptoms lead to a psychotic expression which constitutes a factor of seriousness. Besides, PTSD often induces a risk of substance use disorder supplying psychotic symptoms. Cannabis increases the hallucinations, cocaine strengthens an underlying paranoid tone, and alcohol implies withdrawal hallucinosis. Moreover, such consumption could be a risk factor for the future development of chronic psychosis. From another point of view, by basing themselves on the plasma dopamine beta-hydroxylase activity, some authors made the analogy between psychotic major depression and PTSD with psychotic features (also characterized as a distinct psychotic subtype of PTSD). However, other studies found no correlation between PTSD with psychotic features and family predisposition for schizophrenia or schizoaffective disorder.

DISCUSSION

The determination of the structure of personality seems fundamental in the understanding of the symptoms. A personality of psychotic structure increases the risk of traumatization and PTSD. At the same time, the fragility of this structure causes an increased sensitivity to the trauma, which takes on a particular echo. Moreover, a trauma can test a latent psychotic structure to reveal its existence. The experience of psychosis may be traumatic in itself for patients with, notably, seclusion and sedation during hospitalization. Lastly, the symptoms of this post-traumatic psychosis will be differentiated from neurological confusion caused by a traumatic brain injury. Clinicians often fail to screen routinely for trauma and PTSD symptoms in patients with severe mental illness because few systematic guidelines exist for the identification and treatment of this comorbidity.

CONCLUSION

The links between psychotic and psycho-traumatic symptoms are complex and multidirectional; this co-occurrence is a factor of seriousness. The clinician, while paying attention to these symptoms, has to distinguish the structure of the personality of the subject to articulate the psychotherapy and the pharmacological treatment. Further investigational studies may determine whether antipsychotics will enhance treatment response in PTSD patients with psychotic features.

摘要

引言

创伤后症状与精神病性症状的共现情况在创伤后的即刻阶段已有充分描述,但也可能是慢性的。这种症状共现情况在文献中很少被研究,通常仅从原发性创伤后应激障碍(PTSD)或原发性精神病的单一角度来探讨,缺乏将精神病性症状和创伤后症状统一在同一疾病分类框架内的整合意愿。患有精神分裂症或分裂情感性障碍的个体报告的创伤和攻击发生率高于一般人群。

文献研究结果

在严重精神疾病队列中已注意到PTSD的高发生率。精神病性现象在慢性PTSD患者中可能是相对常见的表现。

目的

本文的目的是揭示精神病性症状与PTSD症状之间各种理论性的精神病理学方面。在退伍军人人群中,PTSD中的精神病性阳性和阴性症状被描述为通常与战斗相关的妄想性思维和幻觉。

临床研究结果

当具有神经质结构人格的个体患上PTSD时,PTSD症状的强度会导致一种精神病性表现,这构成了一个严重因素。此外,PTSD经常引发物质使用障碍的风险,从而产生精神病性症状。大麻会增加幻觉,可卡因会强化潜在的偏执倾向,而酒精会导致戒断性幻觉。此外,这种物质使用可能是未来慢性精神病发展的一个风险因素。从另一个角度来看,一些作者基于血浆多巴胺β-羟化酶活性,将伴有精神病性特征的重度抑郁与PTSD进行了类比(也被描述为PTSD的一种独特的精神病性子类型)。然而,其他研究发现伴有精神病性特征的PTSD与精神分裂症或分裂情感性障碍的家族易感性之间没有相关性。

讨论

人格结构的确定在理解症状方面似乎至关重要。具有精神病性结构的人格会增加受创伤和患PTSD的风险。同时,这种结构的脆弱性会导致对创伤的敏感性增加,从而产生特殊的反响。此外,一次创伤可以检验潜在的精神病性结构以揭示其存在。对于患者来说,精神病体验本身可能是创伤性的,尤其是在住院期间的隔离和镇静过程中。最后,这种创伤后精神病的症状将与创伤性脑损伤引起的神经错乱相区分。临床医生在严重精神疾病患者中往往未能常规筛查创伤和PTSD症状,因为针对这种共病的识别和治疗几乎没有系统的指南。

结论

精神病性症状与精神创伤性症状之间的联系是复杂且多方向的;这种共现是一个严重因素。临床医生在关注这些症状时,必须区分患者的人格结构,以便明确心理治疗和药物治疗。进一步的研究可能会确定抗精神病药物是否会增强伴有精神病性特征的PTSD患者的治疗反应。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验