Department of Ophthalmology, Ramón y Cajal Hospital, Madrid, Spain.
Cornea. 2012 Feb;31(2):188-90. doi: 10.1097/ICO.0b013e31820ca19e.
We report a case of neovascularization at the interface after a deep anterior lamellar keratoplasty and its regression after a single bevacizumab injection.
Case report.
We present a case of neovascularization and bleeding at the interface 2 days after a deep anterior lamellar keratoplasty for herpetic disease that was completely reversed by a single injection of bevacizumab at the interface.
Corneal neovascularization is a typical sign of herpetic disease and one of the most important risk factors that can contribute to corneal graft failure. Close follow-up of patients at risk is necessary to detect and treat this complication as soon as possible to achieve a good outcome. Bevacizumab seems to be a successful and safe therapeutic option.
我们报告一例深板层角膜移植术后界面新生血管的病例,并观察单次贝伐单抗注射后的消退情况。
病例报告。
我们报告了一例疱疹性疾病行深板层角膜移植术后 2 天出现界面新生血管和出血的病例,通过在界面单次注射贝伐单抗,完全逆转了这一情况。
角膜新生血管是疱疹性疾病的典型表现,也是导致角膜移植失败的最重要危险因素之一。对有风险的患者进行密切随访,以便尽早发现和治疗这种并发症,从而获得良好的结果,这是非常必要的。贝伐单抗似乎是一种成功且安全的治疗选择。