术前放疗治疗 T3、T4/Nx 期高位直肠癌：选择性至关重要。
Preoperative radiation therapy for upper rectal cancer T3,T4/Nx: selectivity essential.
机构信息
Department of Surgery, Section of Surgical Oncology, University Medical Center, University of Arizona, Tucson, AZ, USA.
出版信息
Clin Colorectal Cancer. 2012 Jun;11(2):88-92. doi: 10.1016/j.clcc.2011.06.009. Epub 2011 Dec 6.
PMID:22154165
Abstract
This review explores the current available literature regarding the role of neoadjuvant therapy for upper locally advanced rectal cancers (≥10 cm-15 cm). Although there is a paucity of data evaluating the outcomes of preoperative chemoradiation for upper rectal cancers the authors suggest that T3N0 tumors will not likely benefit from radiation and that treatment of T4N0 should be individualized.
摘要
这篇综述探讨了目前关于局部晚期上直肠肿瘤（≥10cm-15cm）新辅助治疗作用的文献。尽管评估术前放化疗治疗上直肠肿瘤的结果的数据很少，但作者认为 T3N0 肿瘤不太可能受益于放疗，而 T4N0 的治疗应该个体化。
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