中国八种常见风湿病的流行病学：北京的一项大规模横断面调查。

Epidemiology of eight common rheumatic diseases in China: a large-scale cross-sectional survey in Beijing.

机构信息

Department of Rheumatology and Immunology, Peking University People's Hospital, 11 Xizhimen South St, Beijing 100044, China.

出版信息

Rheumatology (Oxford). 2012 Apr;51(4):721-9. doi: 10.1093/rheumatology/ker370. Epub 2011 Dec 16.

DOI:10.1093/rheumatology/ker370

PMID:22179737

Abstract

OBJECTIVE

To investigate the prevalence of eight common rheumatic diseases in a large Chinese population.

METHODS

A population-based epidemiological investigation of the prevalence of eight common rheumatic diseases in a suburb of Beijing was conducted in 14 642 individuals. A community-based survey was carried out using a screening questionnaire. Positive responders were included in a clinical and laboratory examination. Diagnosis was based on the criteria of ACR or those used widely in literature.

RESULTS

A total of 10 556 inhabitants were interviewed. Forty-three cases of RA were identified with an age-adjusted prevalence of 0.28% (95% CI 0.19%, 0.41%). Gout was diagnosed with a crude prevalence of 0.09% (95% CI 0.05%, 0.17%). Psoriasis was reported in 28 individuals with a prevalence of 0.27% (95% CI 0.18%, 0.38%). This included two cases diagnosed with PsA, resulting in a prevalence of 7.14% (95% CI 0.88%, 23.5%) in psoriasis patients and 0.02% (95% CI 0%, 0.07%) in the general population. Three individuals were identified with SLE, with a prevalence of 0.03% (95% CI 0%, 0.06%). One individual was identified with SSc and the calculated prevalence was 0.01% (95% CI 0%, 0.05%). One case of Behçet's disease was identified, giving a prevalence of 0.01% (95% CI 0%, 0.05%).

CONCLUSION

This large-scale epidemiological survey provides an estimate of the burden of rheumatic diseases in China.

摘要

目的

调查中国某大城市人群中八种常见风湿性疾病的患病率。

方法

对北京郊区 14642 人进行了一项基于人群的、针对八种常见风湿性疾病患病率的流行病学调查。采用筛选问卷进行社区调查。对阳性应答者进行临床和实验室检查。诊断基于 ACR 标准或文献中广泛使用的标准。

结果

共访谈了 10556 名居民。发现 43 例 RA，经年龄校正后的患病率为 0.28%（95%CI 0.19%，0.41%）。痛风的粗患病率为 0.09%（95%CI 0.05%，0.17%）。报告了 28 例银屑病，患病率为 0.27%（95%CI 0.18%，0.38%）。其中包括两例诊断为银屑病关节炎的病例，导致银屑病患者的患病率为 7.14%（95%CI 0.88%，23.5%），普通人群患病率为 0.02%（95%CI 0%，0.07%）。发现 3 例 SLE，患病率为 0.03%（95%CI 0%，0.06%）。发现 1 例硬皮病，计算的患病率为 0.01%（95%CI 0%，0.05%）。发现 1 例贝赫切特病，患病率为 0.01%（95%CI 0%，0.05%）。