Van Opstal Nick, Verheyden Frank
Department of Orthopaedic Surgery, Heilig Hart Hospital, Lier, Belgium.
Acta Orthop Belg. 2011 Oct;77(5):691-5.
Materials currently used for total knee arthroplasty (TKA) are well known for their good biocompatibility, but corrosion of the implant and metal ion release may elicit an immune response in the periprosthetic tissue. Its role in the outcome of the implant remains a subject of discussion. Metal sensitivity after joint replacement is frequent, but few patients exhibit symptoms. Nickel, cobalt and chromium are the most common sensitizers, but allergic reactions to titanium and vanadium have also been described. We present a case of a 46-year old woman with persistent dermatitis following TKA revision with an oxidized zirconium (oxinium) femoral component and Ti6Al4V tibial baseplate. After revision with a customized oxinium tibial component, symptoms resolved completely.
目前用于全膝关节置换术(TKA)的材料以其良好的生物相容性而闻名,但植入物的腐蚀和金属离子释放可能会在假体周围组织中引发免疫反应。其在植入物结果中的作用仍是一个讨论的话题。关节置换术后金属过敏很常见,但很少有患者出现症状。镍、钴和铬是最常见的致敏剂,但也有对钛和钒过敏反应的描述。我们报告一例46岁女性患者,在使用氧化锆(钇稳定氧化锆)股骨部件和Ti6Al4V胫骨基板进行TKA翻修术后出现持续性皮炎。在用定制的钇稳定氧化锆胫骨部件翻修后,症状完全缓解。