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蝶骨大翼儿童骨肉瘤:病例报告及文献复习

Childhood osteosarcoma of greater wing of sphenoid: case report and review of literature.

作者信息

Meel Rachna, Thulkar Sanjay, Sharma Mehar Chand, Jagadesan Pandjatcharan, Mohanti Bidhu Kalyan, Sharma Suresh Chandra, Bakhshi Sameer

机构信息

Oculoplastics and Ocular Oncology Service, Department of Medical Oncology, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Pediatr Hematol Oncol. 2012 Mar;34(2):e59-62. doi: 10.1097/MPH.0b013e3182331f5a.

Abstract

Primary osteosarcoma of skull base is extremely rare. We present a case of primary osteosarcoma arising in greater wing of sphenoid in a child. Our patient had an incomplete excision after which he received adjuvant chemotherapy and radiotherapy. There was good response to adjuvant chemoradiotherapy and the patient is disease free at a follow-up of 18 months. Treatment of skull base osteosarcomas is difficult, as complete excision is often not possible. To the best of our knowledge, this is the first case of sphenoid wing osteosarcoma in childhood to be reported in literature.

摘要

颅底原发性骨肉瘤极为罕见。我们报告一例儿童蝶骨大翼原发性骨肉瘤病例。我们的患者接受了不完全切除,术后接受了辅助化疗和放疗。辅助放化疗反应良好,患者在18个月的随访中无疾病。颅底骨肉瘤的治疗很困难,因为通常无法完全切除。据我们所知,这是文献中报道的首例儿童蝶骨翼骨肉瘤病例。

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