Simić Dubravka, Topić Ivana, Penavić Jasna Zeljko
Department for Dermatology and Venerology, Mostar University Clinical Hospital, Bosnia and Herzegovina.
Coll Antropol. 2011 Sep;35 Suppl 2:137-40.
Incidence rate of cutaneous malignant melanoma (MM), one of the most aggressive skin tumours, is increasing nowadays. Etiology of MM has not been fully understood. Various etiological factors are of relevance for the occurrence of the disease. The solar radiation as well as long term exposure to ultraviolet radiation has the greatest impact on development of this skin tumour. Melanoma risk factors have different associations with melanoma on body sites. This study investigates the epidemiological and clinical characteristics of MM such as age, gender, distribution of MM on the body and type of melanoma in the area of West Herzegovina, on the sample of 205 patients. It presents the occurrence of MM in the period from 1997. to 2010. Both, females and males have increased the risk of melanoma on the trunk (45.9%). Different body sites receive various amounts of sun exposure, yet melanomas occur on all parts of the body. This may represent different pathways in the etiology of melanoma based on body location. The most frequent type of MM was superficial spreading melanoma (SSM) 47.8%. According to our investigation incidence rate was 18.6% (per 1000 patients).
皮肤恶性黑色素瘤(MM)是最具侵袭性的皮肤肿瘤之一,其发病率目前正在上升。MM的病因尚未完全明确。多种病因因素与该疾病的发生相关。太阳辐射以及长期暴露于紫外线辐射对这种皮肤肿瘤的发展影响最大。黑色素瘤风险因素与身体不同部位的黑色素瘤有不同关联。本研究以205例患者为样本,调查了黑塞哥维那西部地区MM的流行病学和临床特征,如年龄、性别、MM在身体上的分布以及黑色素瘤类型。它呈现了1997年至2010年期间MM的发病情况。男性和女性躯干上患黑色素瘤的风险均有所增加(45.9%)。身体不同部位接受的阳光照射量不同,但黑色素瘤可发生于身体的所有部位。这可能代表了基于身体部位的黑色素瘤病因的不同途径。最常见的MM类型是浅表扩散性黑色素瘤(SSM),占47.8%。根据我们的调查,发病率为18.6%(每1000例患者)。