利用瞬态诱发耳声发射评估家族性地中海热患儿的耳蜗功能。
Evaluation of cochlear function using transient evoked otoacoustic emission in children with Familial Mediterranean Fever.
作者信息
Uysal Ismail Önder, Gürbüzler Levent, Kaya Ali, Koç Sema, Gültürk Sefa, Cevit Omer, Müderris Suphi
机构信息
Department of Otorhinolaryngology, Cumhuriyet University School of Medicine, Sivas, Turkey.
出版信息
Int J Pediatr Otorhinolaryngol. 2012 Mar;76(3):379-81. doi: 10.1016/j.ijporl.2011.12.015. Epub 2012 Jan 9.
OBJECTIVE
The aim of this study was to investigate cochlear functions in children with Familial Mediterranean Fever (FMF).
METHODS
Fifty-six FMF patients (112 ears) and 30 healthy control subjects (60 ears) were included in the study. Transient evoked otoacoustic emission (TEOAE) was investigated. Numerical measurements of TEOAE, except the correlation percentage (%), included response amplitude (dB) and signal/noise (SN) ratio.
RESULTS
There was no statistically significant difference in age and sex in the two groups. Mean TEOAE correlation percentage, signal/noise ratio, TEOAE amplitudes in 1, 1.5, 2, 3 and 4 Hz frequency values were not different between the two groups (p>0.05).
CONCLUSIONS
In this study using the TEOAE test, we found that FMF did not cause outer cell hair damage in children. In the literature, there is no study on outer cell hair damage in children or adults with FMF, so this is the first investigational study.
目的
本研究旨在调查家族性地中海热（FMF）患儿的耳蜗功能。
方法
本研究纳入了56例FMF患者（112耳）和30名健康对照者（60耳）。对瞬态诱发耳声发射（TEOAE）进行了研究。TEOAE的数值测量，除相关百分比（%）外，还包括反应幅度（dB）和信号/噪声（SN）比。
结果
两组在年龄和性别上无统计学显著差异。两组之间，平均TEOAE相关百分比、信号/噪声比、1、1.5、2、3和4Hz频率值下的TEOAE幅度均无差异（p>0.05）。
结论
在本项使用TEOAE测试的研究中，我们发现FMF不会导致儿童外毛细胞损伤。在文献中，尚无关于FMF患儿或成人外毛细胞损伤的研究，因此这是第一项调查研究。
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