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[原位喂养矿物质不均衡日粮大鼠软组织和骨骼中镁与锌分布的相似性]

[Resemblance of magnesium and zinc distribution in soft tissues and bone of rats fed unbalanced mineral diets in situ].

作者信息

Yasui M, Yase Y, Shimizu E, Ota K

机构信息

Division of Neurological Diseases, Wakayama Medical College, Japan.

出版信息

No To Shinkei. 1990 Jul;42(7):635-42.

PMID:2223259
Abstract

Although the role of zinc (Zn) and magnesium (Mg) in situ may be of a critical importance in replication, transcription and repair of DNA, to our knowledge, the relationship between Mg and Zn has been described. This study, therefore, was designed experimentally to investigate the relationship between Mg and Zn in soft tissues and bone of rats after fortification of unbalanced mineral diets, and minerals and metals in soft tissues and bone were determined by inductively coupled plasma emission spectrometry. In the groups fed low calcium (Ca) diet, low Ca-Mg diet and low Ca-Mg plus high Al diet, serum Mg level was lower in the group fed low Ca-Mg diet and low Ca-Mg plus high Al diet than those in the groups fed standard diet and low Ca diet. However, there was no significant difference in Mg content of CNS tissues in rats fed unbalanced and standard diets except for that in the spinal cord of rats fed low Ca-Mg plus high Al diet. Whereas, Zn content of CNS showed lower values in the unbalanced mineral diet groups, especially in all CNS regions of the low Ca-Mg plus high Al diet group, than those in the standard and the low Ca diet group. And Zn contents in heart, kidney and abdominal aorta of rats fed low Ca-Mg diet and low Ca-Mg plus high Al diet were more decreased than those of the standard and the low Ca diet groups.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

尽管锌(Zn)和镁(Mg)在DNA复制、转录和修复过程中的原位作用可能至关重要,但据我们所知,Mg和Zn之间的关系尚未见描述。因此,本研究通过实验设计,旨在探究在不均衡矿物质饮食强化后,大鼠软组织和骨骼中Mg与Zn的关系,并采用电感耦合等离子体发射光谱法测定软组织和骨骼中的矿物质与金属含量。在低钙(Ca)饮食组、低钙-镁饮食组以及低钙-镁加高铝饮食组中,低钙-镁饮食组和低钙-镁加高铝饮食组的血清镁水平低于标准饮食组和低钙饮食组。然而,除了低钙-镁加高铝饮食组大鼠脊髓外,不均衡饮食组和标准饮食组大鼠中枢神经系统组织中的镁含量并无显著差异。而在不均衡矿物质饮食组中,尤其是低钙-镁加高铝饮食组的所有中枢神经系统区域,中枢神经系统的锌含量低于标准饮食组和低钙饮食组。并且,低钙-镁饮食组和低钙-镁加高铝饮食组大鼠心脏、肾脏和腹主动脉中的锌含量比标准饮食组和低钙饮食组下降得更多。(摘要截断于250字)

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