关于使用PRESAGE/光学计算机断层扫描验证近距离放射治疗源附近三维剂量测定的可行性
On the Feasibility of Verification of 3D Dosimetry Near Brachytherapy Sources Using PRESAGE/Optical-CT.
作者信息
Pierquet M, Craciunescu O, Steffey B, Song H, Oldham M
机构信息
Duke University Medical Center, Durham, NC, 27710.
出版信息
J Phys Conf Ser. 2010 Dec 7;250(1):120911-120915. doi: 10.1088/1742-6596/250/1/012091.
PURPOSE
The feasibility of using the PRESAGE/Optical-CT system for 3D dosimetry verification around a brachytherapy source is investigated. METHOD AND MATERIALS: Brachytherapy dose distributions were obtained by irradiation of cylindrical PRESAGE volumes 6cm in diameter by 8cm height with a GammaMed 12i Ir-192 HDR unit (Varian Medical Systems). A narrow channel on the central axis was created by setting a steel catheter in the Presage during manufacture, enabling measurements close to the source (~3mm). RESULTS: Comparison of dose line profiles shows good agreement between PRESAGE and verified calculated dose calculation, in both high and low dose regions. CONCLUSION: The PRESAGE/Optical-CT shows good potential in verification of 3D dose distributions around brachytherapy sources.
目的
研究使用PRESAGE/光学计算机断层扫描（Optical-CT）系统对近距离放射治疗源周围进行三维剂量测定验证的可行性。方法和材料：使用瓦里安医疗系统公司的伽马Med 12i铱-192高剂量率（HDR）装置，对直径6厘米、高8厘米的圆柱形PRESAGE体模进行照射，从而获得近距离放射治疗剂量分布。在制造过程中，通过在PRESAGE中设置一根钢导管，在中心轴上创建一个狭窄通道，以便在靠近源（约3毫米）处进行测量。结果：剂量线轮廓的比较表明，在高剂量和低剂量区域，PRESAGE与经过验证的计算剂量计算结果之间具有良好的一致性。结论：PRESAGE/光学计算机断层扫描在验证近距离放射治疗源周围三维剂量分布方面显示出良好的潜力。
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