Neuroimage. 2012 Aug 15;62(2):1014-6. doi: 10.1016/j.neuroimage.2012.01.019. Epub 2012 Jan 8.
Understanding and quantifying dynamic susceptibility contrast, which arises from compartmentalized magnetic field perturbers (e.g., deoxyhemoglobin, contrast agents) that affect the water around them, formed the basis of a significant part of the author's fMRI-related research in the early 90's. This short note describes how the scientific work used to help understand and quantify dynamic injections of contrast agents, primarily designed for clinical MRI, was adapted to help quantify and explain BOLD imaging.
理解和量化源于分隔的磁场扰动物(例如,脱氧血红蛋白、造影剂)的动态磁敏感对比,这些扰动物会影响它们周围的水,这构成了作者在 90 年代早期与 fMRI 相关研究的重要部分的基础。这篇简短的说明描述了如何将主要用于临床 MRI 的造影剂动态注射的科学工作进行改编,以帮助量化和解释 BOLD 成像。