Ramzan Mohammed, Yadav Satya Prakash, Bhalla Sunita, Jamwal Pallavi, Grover A K, Sachdeva Anupam
Pediatric Hematology Oncology and Bone Marrow Transplant Unit, Center for Child Health, Sir Ganga Ram Hospital, Delhi, India.
J Pediatr Hematol Oncol. 2012 May;34(4):e158-60. doi: 10.1097/MPH.0b013e3182332281.
Langerhans cell histiocytosis occurring as an isolated tumor of eyelid has rarely been reported. We report an unusual case of a 5-year-old boy who presented with a smooth nodular lesion over the right lower eyelid accompanied with hyperemia for a month. The biopsy and CD1a positivity confirmed it to be Langerhans cell histiocytosis. It was localized to the eyelid as no other organ was involved. Although Langerhans cell histiocytosis of the eyelid is exceptional, it must be included in the differential diagnosis of eyelid nodular lesions and the diagnostic and the subsequent management must be multidisciplinary.
作为眼睑孤立性肿瘤出现的朗格汉斯细胞组织细胞增多症鲜有报道。我们报告一例罕见病例,一名5岁男孩,右眼下眼睑出现一个光滑的结节性病变并伴有充血,持续1个月。活检及CD1a阳性证实为朗格汉斯细胞组织细胞增多症。由于未累及其他器官,病变局限于眼睑。尽管眼睑朗格汉斯细胞组织细胞增多症较为罕见,但在眼睑结节性病变的鉴别诊断中必须考虑到,诊断及后续治疗必须采取多学科方法。