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在初级保健中实施他汀类药物转换方案:患者的观点和经验。

Implementing a statin switching programme in primary care: patients' views and experiences.

机构信息

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.

出版信息

Br J Clin Pharmacol. 2012 Jul;74(1):147-53. doi: 10.1111/j.1365-2125.2012.04183.x.

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT

• Switching of patients' prescribed medicines within a therapeutic class is a common strategy to reduce prescribing costs, and in England a standard methodology has been promoted for switching processes. • Previous work to date suggests many patients are sceptical of generic products and switching may reduce compliance. • Patients' views on switching in general and the processes used have not been widely sought.

WHAT THIS STUDY ADDS

• Patients may be less accepting of therapeutic switching programmes than is currently assumed. • Patients lacked understanding of the reason for the switch, despite standard letters and information leaflets being used, and few sought consultations. • Greater explanation of switching, possibly with involvement of community pharmacists, could lead to improved patient understanding and acceptance. INTRODUCTION Estimates suggest £200 million could be saved on prescribing costs in England by implementing medication switches. Few studies have evaluated patients' views or understanding of therapeutic switches.

AIM

To obtain patient and pharmacist perspectives on switching from atorvastatin to simvastatin within an English Primary Care Trust (PCT).

METHOD

All patients undergoing this switch, in seven self-selected East Lancashire practices, were sent postal questionnaires covering demographics, experiences and views regarding switching, with no reminder. Practice pharmacists implementing switches in these practices were interviewed about processes and their views on these.

RESULTS

Pharmacists' switching process involved a standard letter offering a telephone consultation or appointment, plus an information leaflet. They considered most patients accepted switches, with few requesting consultations. Four hundred and ninety-four patients were identified and a response rate of 48.6% (240) obtained. The majority of respondents were happy with the switch (53.7%) and how they were informed (60.1%), with these findings being positively correlated. However over half (52.9%) did not understand the reason for the switch, particularly those with lower educational qualifications. Patients unhappy about switching perceived they had experienced side effects, or only learned of the switch on collecting a prescription or did not recall the consultation offer. Respondents indicated a preference for future switches to involve a face-to-face consultation (59.8%), with two-thirds (65.2%) agreeing that community pharmacists should explain medication switches.

CONCLUSION

The standard process used, in line with nationally-designed templates, resulted in many patients being unhappy with or lacking understanding of switching statins, suggesting that improvements may be needed.

摘要

关于这个主题,已经有一些已知的信息:

  • 在治疗类别内转换患者处方药物是降低处方费用的常用策略,在英国,已经推广了一种标准方法用于转换过程。

  • 迄今为止的先前工作表明,许多患者对仿制药持怀疑态度,而转换可能会降低依从性。

  • 患者对一般转换过程的看法以及所使用的过程尚未广泛征求意见。

这项研究的结果是什么

  • 与目前的假设相比,患者可能对治疗性转换方案的接受程度较低。

  • 尽管使用了标准信件和信息传单,但患者仍然不理解转换的原因,很少寻求咨询。

  • 更充分地解释转换,可能涉及社区药剂师,可能会提高患者的理解和接受程度。

引言

估计通过实施药物转换,英国可以节省 2 亿英镑的处方费用。很少有研究评估过患者对治疗性转换的看法或理解。

目的

获得英格兰一家初级保健信托基金(PCT)中阿托伐他汀转换为辛伐他汀的患者和药剂师的观点。

方法

在七个自行选择的东兰开夏郡实践中进行此转换的所有患者均收到了涵盖人口统计学,经验和对转换的看法的邮寄问卷,并且没有任何提醒。实施这些实践中转换的实践药剂师接受了有关转换过程及其对这些过程的看法的采访。

结果

药剂师的转换过程包括提供电话咨询或预约的标准信件,外加一份信息传单。他们认为大多数患者都接受了转换,很少有人要求咨询。确定了 494 名患者,获得了 48.6%(240 名)的回复率。大多数受访者对转换感到满意(53.7%),并且对信息传递方式感到满意(60.1%),这两个发现呈正相关。但是,超过一半(52.9%)的人不了解转换的原因,特别是那些教育程度较低的人。对转换不满意的患者认为他们已经经历了副作用,或者只是在领取处方时才了解到转换,或者不记得咨询的提议。受访者表示希望将来的转换涉及面对面咨询(59.8%),三分之二(65.2%)的人同意社区药剂师应解释药物转换。

结论

按照国家设计的模板使用的标准流程导致许多患者对转换他汀类药物感到不满或缺乏了解,这表明可能需要改进。

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本文引用的文献

1
Generic and therapeutic substitutions in the UK: are they a good thing?
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Br J Clin Pharmacol. 2005 May;59(5):564-73. doi: 10.1111/j.1365-2125.2005.02355.x.

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