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何为活跃型肢端肥大症,我们有哪些参数?

What is active acromegaly and which parameters do we have?

机构信息

Department of Medicine, Section Endocrinology, Erasmus University Medical Center Rotterdam, CA Rotterdam, The Netherlands.

出版信息

Clin Endocrinol (Oxf). 2012 May;76(5):609-14. doi: 10.1111/j.1365-2265.2012.04346.x.

Abstract

Disease activity of acromegaly can be measured in many ways. Growth hormone (GH) and insulin-like growth factor 1 (IGF1) concentrations are the main biochemical markers used to measure the response to treatment. Both GH and IGF1 have been associated with prognosis, in particular mortality. In this review, we discuss the available parameters to assess disease activity in acromegaly.

摘要

肢端肥大症的疾病活动度可以通过多种方式进行测量。生长激素(GH)和胰岛素样生长因子 1(IGF1)浓度是用于测量治疗反应的主要生化标志物。GH 和 IGF1 均与预后相关,特别是与死亡率相关。在这篇综述中,我们讨论了评估肢端肥大症疾病活动度的可用参数。

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