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米兰正在发生的一些事:第四届国际博士生癌症会议综述

Something going on in Milan: a review of the 4th International PhD Student Cancer Conference.

作者信息

Segré C

机构信息

European School of Molecular Medicine, IFOM-IEO Campus, via Adamello 16, 20081, Milan, Italy.

出版信息

Ecancermedicalscience. 2010;4:198. doi: 10.3332/ecancer.2010.198. Epub 2010 Nov 10.

Abstract

The 4th International PhD Student Cancer Conference was held at the IFOM-IEO-Campus in Milan from 19-21 May 2010 http://www.semm.it/events_researchPast.phpThe Conference covered many topics related to cancer, from basic biology to clinical aspects of the disease. All attendees presented their research, by either giving a talk or presenting a poster. This conference is an opportunity to introduce PhD students to top cancer research institutes across Europe.THE CORE PARTICIPANTING INSTITUTES INCLUDED: European School of Molecular Medicine (SEMM)-IFOM-IEO Campus, MilanBeatson Institute for Cancer Research (BICR), GlasgowCambridge Research Institute (CRI), Cambridge, UKMRC Gray Institute of Radiation Biology (GIROB), OxfordLondon Research Institute (LRI), LondonPaterson Institute for Cancer Research (PICR), ManchesterThe Netherlands Cancer Institute (NKI), Amsterdam'You organizers have crushed all my prejudices towards Italians. Congratulations, I enjoyed the conference immensely!' Even if it might have sounded like rudeness for sure this was supposed to be a genuine compliment (at least, that's how we took it), also considering that it was told by a guy who himself was the fusion of two usually antithetical concepts: fashion style and English nationality.The year 2010 has marked an important event for Italian research in the international scientific panorama: the European School of Molecular Medicine (SEMM) had the honour to host the 4th International PhD Student Cancer Conference, which was held from 19-21 May 2010 at the IFOM-IEO-Campus (http://www.semm.it/events_researchPast.php) in Milan.The conference was attended by more than one hundred students, coming from a selection of cutting edge European institutes devoted to cancer research. The rationale behind it is the promotion of cooperation among young scientists across Europe to debate about science and to exchange ideas and experiences. But that is not all, it is also designed for PhD students to get in touch with other prestigious research centres and to create connections for future post docs or job experiences. And last but not least, it is a golden chance for penniless PhD students to spend a couple of extra days visiting a foreign country (this motivation will of course never be voiced to supervisors).The network of participating institutes has a three-nation core, made up of the Netherlands Cancer Institute, the Italian European School of Molecular Medicine (SEMM) and five UK Cancer Research Institutes (The London Research Institute, The Cambridge Research Institute, The Beatson Institute for Cancer Research in Glasgow, The Patterson Institute for Cancer Research in Manchester and the MRC Gray Institute for Radiation Oncology and Biology in Oxford).The conference is hosted and organised every year by one of the core institutes; the first was in Cambridge in 2007, Amsterdam in 2008 and London in 2009, this year was the turn of Milan.In addition to the core institutes, PhD students from several other high-profile institutes are invited to attend the conference. This year participants applied from the Spanish National Cancer Centre (CNIO, Madrid), the German Cancer Research Centre (DKFZ, Heidelberg), the European Molecular Biology Labs (EMBL, Heidelberg) and the San Raffaele Institute (HSR, Milan). Moreover four 'special guests' from the National Centre for Biological Sciences of Bangalore (India) attended the conference in Milan. This represents a first step in widening the horizons beyond Europe into a global worldwide network of talented PhD students in life sciences.The conference spread over two and a half days (Wednesday 19th to Friday 21st May) and touched on a broad spectrum of topics: from basic biology to development, from cancer therapies to modelling and top-down new generation global approaches. The final selection of presentations has been a tough task for us organisers (Chiara Segré, Federica Castellucci, Francesca Milanesi, Gianluca Varetti and Gian Maria Sarra Ferraris), due to the high scientific level of the abstracts submitted. In the end, 26 top students were chosen to give a 15-min oral presentation in one of eight sessions: Development & Differentiation, Cell Migration, Immunology & Cancer, Modelling & Large Scale approaches, Genome Instability, Signal Transduction, Cancer Genetics & Drug Resistance, Stem Cells in Biology and Cancer.The scientific programme was further enriched by two scientific special sessions, held by Professor Pier Paolo di Fiore and Dr Giuseppe Testa, Principal Investigators at the IFOM-IEO-Campus and by a bioethical round table on human embryonic stem cell research moderated by Silvia Camporesi, a senior PhD student in the SEMM PhD Programme 'Foundation of Life Science and their Bioethical Consequences'.ON TOP OF EVERYTHING, WE HAD THE PLEASURE OF INVITING, AS KEYNOTE SPEAKERS, TWO LEADING EUROPEAN SCIENTISTS IN THE FIELDS OF CANCER INVASION AND BIOLOGY OF STEM CELLS, RESPECTIVELY: Dr Peter Friedl from The Nijmegen Centre for Molecular Life (The Netherlands) and Professor Andreas Trumpp from The Heidelberg Institute for Stem Cell Technology and Experimental Medicine (Heidelberg).All the student talks have distinguished themselves for the impressive quality of the science; an encouraging evidence of the high profile level of research carried out in Europe. It would be beyond the purposes of this report to summarise all 26 talks, which touched many different and specific topics. For further information, the Conference Abstract book with all the scientific content is available on the conference Web site (http://www.semm.it/events_researchPast.php). In what follows, the special sessions and the keynote lectures will be discussed in detail.

摘要

第四届国际博士生癌症会议于2010年5月19日至21日在米兰的IFOM - IEO校园举行(http://www.semm.it/events_researchPast.php)。会议涵盖了许多与癌症相关的主题,从基础生物学到该疾病的临床方面。所有参会者都通过演讲或展示海报的方式展示了他们的研究成果。本次会议为博士生们提供了一个向欧洲顶尖癌症研究机构进行介绍的机会。

核心参与机构包括

欧洲分子医学学院(SEMM) - IFOM - IEO校园,米兰

贝茨森癌症研究所(BICR),格拉斯哥

剑桥研究所(CRI),英国剑桥

医学研究理事会格雷辐射生物学研究所(GIROB),牛津

伦敦研究所(LRI),伦敦

帕特森癌症研究所(PICR),曼彻斯特

荷兰癌症研究所(NKI),阿姆斯特丹

“你们组织者打破了我对意大利人的所有偏见。恭喜,我非常享受这次会议!” 即便这话听起来可能确实像是无礼,但这应该是由衷的赞美(至少,我们是这么理解的),况且说这话的人本身融合了两个通常对立的概念:时尚风格与英国国籍。

2010年对意大利科研在国际科学领域而言是一个重要事件:欧洲分子医学学院(SEMM)有幸主办了第四届国际博士生癌症会议,该会议于2010年5月19日至21日在米兰的IFOM - IEO校园(http://www.semm.it/events_researchPast.php)举行。

此次会议有来自欧洲致力于癌症研究的顶尖机构的一百多名学生参加。其背后的理念是促进欧洲年轻科学家之间的合作,以便就科学进行辩论并交流想法和经验。但这还不止,它还旨在让博士生与其他著名研究中心建立联系,并为未来的博士后或工作经历创造机会。最后但同样重要的是,对于身无分文的博士生来说,这是一个额外花几天时间游览外国的绝佳机会(当然,这种动机永远不会向导师表露)。

参与机构网络有一个由三个国家组成的核心,包括荷兰癌症研究所、意大利的欧洲分子医学学院(SEMM)以及五个英国癌症研究机构(伦敦研究所、剑桥研究所、格拉斯哥的贝茨森癌症研究所、曼彻斯特的帕特森癌症研究所和牛津的医学研究理事会格雷肿瘤学与生物学研究所)。

该会议每年由其中一个核心机构主办和组织;第一次会议于2007年在剑桥举行,2008年在阿姆斯特丹,2009年在伦敦,今年轮到米兰。

除了核心机构外,还邀请了来自其他几个知名机构的博士生参加会议。今年有来自西班牙国家癌症研究中心(CNIO,马德里)、德国癌症研究中心(DKFZ,海德堡)、欧洲分子生物学实验室(EMBL,海德堡)和圣拉斐尔研究所(HSR,米兰)的学生申请参会。此外,来自印度班加罗尔国家生物科学中心的四位 “特邀嘉宾” 参加了在米兰举行的会议。这是将视野从欧洲扩展到全球生命科学领域优秀博士生全球网络的第一步。

会议持续了两天半(5月19日星期三至5月21日星期五),涉及广泛的主题:从基础生物学到发育,从癌症治疗到建模以及自上而下的新一代全球方法。对于我们组织者(基娅拉·塞格雷、费德里卡·卡斯特卢奇、弗朗西斯卡·米拉内西、詹卢卡·瓦雷蒂和吉安·玛丽亚·萨拉·费拉里斯)来说,最终确定演讲内容是一项艰巨的任务,因为提交的摘要科学水平很高。最终,26名优秀学生被选中在八个分会场之一进行15分钟的口头报告:发育与分化、细胞迁移、免疫学与癌症、建模与大规模方法、基因组不稳定、信号转导、癌症遗传学与耐药性、生物学和癌症中的干细胞。

科学计划因两场科学特别会议而进一步丰富,这两场会议分别由IFOM - IEO校园的首席研究员皮尔·保罗·迪·菲奥雷教授和朱塞佩·泰斯塔博士主持,还有一场关于人类胚胎干细胞研究的生物伦理圆桌会议,由SEMM博士项目 “生命科学基础及其生物伦理后果” 的高级博士生西尔维娅·坎波雷西主持。

最重要的是,我们有幸邀请了癌症侵袭领域和干细胞生物学领域的两位欧洲顶尖科学家作为主旨演讲人:来自荷兰奈梅亨分子生命中心的彼得·弗里德尔博士和来自海德堡干细胞技术与实验医学研究所的安德烈亚斯·特朗普教授。

所有学生的报告都因其令人印象深刻的科学质量而脱颖而出;这是欧洲高水平研究的一个令人鼓舞的证明。总结这26场涉及许多不同和特定主题的报告超出了本报告的目的。如需进一步信息,包含所有科学内容的会议摘要集可在会议网站(http://www.semm.it/events_researchPast.php)上获取。以下将详细讨论特别会议和主旨演讲。

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