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分析痴呆症患者的个案管理计划:系统评价。

Analysis of case management programs for patients with dementia: a systematic review.

机构信息

Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Gériatrie, Paris, France.

出版信息

Alzheimers Dement. 2012 Sep;8(5):426-36. doi: 10.1016/j.jalz.2011.06.004. Epub 2012 Jan 30.

Abstract

BACKGROUND

People suffering from dementia are particularly vulnerable to the gaps between the health and social service systems. Case management is a professional field that seeks to fill in these gaps and remedy this fragmentation.

METHODS

We report the results of a systematic literature review of the impact of case management programs on clinical outcomes and the utilization of resources by persons with dementia. We focused on randomized controlled trials (RCTs) and attempted to identify the factors that might contribute to greater program efficacy. Because the evaluation methods in these studies varied, we used the effect size method to estimate the magnitude of the statistically significant effects reported.

RESULTS

Our search strategy identified 17 references relating to six RCTs. Four of these six RCTs reported moderately statistically significant effects (effect size, 0.2-0.8) on their primary end point: the clinical outcome in three and resource utilization in one. Two of the RCTs reported weak or no effects (effect size, <0.2) on their primary end point. Because of the wide variety of the end points used, an overall effect size could not be calculated. Parameters that appear to be related to greater case management efficacy are the integration level between the health and social service organizations and the intensity of the case management.

CONCLUSIONS

Integration and case management intensity seem to determine the magnitude of the clinical effects in this new professional field. Further studies are needed to clarify the economic impact.

摘要

背景

患有痴呆症的人特别容易受到卫生和社会服务系统之间差距的影响。个案管理是一个专业领域,旨在填补这些差距并弥补这种碎片化。

方法

我们报告了对个案管理计划对痴呆症患者的临床结果和资源利用的影响进行系统文献综述的结果。我们专注于随机对照试验(RCT),并试图确定可能有助于提高计划效果的因素。由于这些研究中的评估方法不同,我们使用效应量方法来估计报告的具有统计学意义的影响的大小。

结果

我们的搜索策略确定了 17 篇与六项 RCT 相关的参考文献。这六项 RCT 中的四项报告了其主要终点的中度统计学显著影响(效应量为 0.2-0.8):三项为临床结果,一项为资源利用。两项 RCT 报告了对其主要终点的弱或无影响(效应量<0.2)。由于所使用的终点非常多样化,因此无法计算总体效应量。似乎与更高的个案管理效果相关的参数是卫生和社会服务组织之间的整合水平和个案管理的强度。

结论

整合和个案管理强度似乎决定了这个新专业领域临床效果的大小。需要进一步研究来阐明其经济影响。

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