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美国苗族社区因氰化物珠宝清洁剂中毒和自杀:病例系列。

Poisoning and suicide by cyanide jewelry cleaner in the US Hmong community: a case series.

机构信息

Hennepin Regional Poison Center, Minneapolis/St. Paul, MN, USA.

出版信息

Clin Toxicol (Phila). 2012 Feb;50(2):136-40. doi: 10.3109/15563650.2011.650173. Epub 2012 Jan 31.

Abstract

Over 200 000 persons of Hmong ethnicity live in the United States. The majority of this Southeast Asian ethnic group live in California, Minnesota and Wisconsin. Tradition plays a strong role in the Hmong population, and difficulty in assimilation into "Western ways" has been reported to result in depression and suicide attempts. Some products sold at Southeast Asian ethnic markets are well-known within the Hmong community to be lethal but are essentially unknown to the outside community. We describe eight cases in which cyanide-containing products were ingested by Hmong patients. Seven cases were suicide attempts involving the ingestion of a locally-purchased substance intended for cleaning metal, coins, or jewelry. One case involved the fatal ingestion of a cyanide-containing "herbal" cure. In the majority of the cases, cyanide was not initially suspected, and treatment was delayed due to lack of information regarding the product ingested. In the two patients who survived, the cyanide antidote kit (sodium nitrite, amyl nitrite, and sodium thiosulfate) was administered early. Clinicians should be aware that unusual and potentially lethal products are easily available at ethnic markets. Cyanide toxicity should be suspected, and empiric antidote therapy initiated early, in patients of Hmong or Southeast Asian descent who present with sudden and unexplained cardiovascular collapse and metabolic acidosis, especially in the setting of a suspected suicidal ingestion.

摘要

超过 20 万苗族裔人口居住在美国。这个东南亚族群的大多数人居住在加利福尼亚、明尼苏达和威斯康星。传统在苗族中扮演着重要的角色,难以融入“西方方式”被报道为导致抑郁和自杀企图的原因。一些在东南亚族裔市场上销售的产品在苗族社区中众所周知是致命的,但对外部社区来说基本上是未知的。我们描述了 8 例苗族患者摄入含氰化物产品的案例。7 例是自杀企图,涉及摄入一种用于清洁金属、硬币或珠宝的本地购买的物质。一例涉及致命摄入含氰化物的“草药”治疗。在大多数情况下,最初并未怀疑氰化物,并且由于对摄入的产品缺乏信息,治疗被延迟。在两名幸存的患者中,早期给予了氰化物解毒剂套件(亚硝酸钠、亚硝酸戊酯和硫代硫酸钠)。临床医生应该意识到,在出现突然和不明原因的心血管崩溃和代谢性酸中毒的苗族或东南亚裔患者中,尤其是在疑似自杀性摄入的情况下,应怀疑氰化物毒性,并尽早开始经验性解毒治疗。

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