Department of Obstetrics and Gynecology,Medical University Vienna, Wahringer Gurtel ,Vienna, Austria.
Arch Gynecol Obstet. 2012 Jul;286(1):37-41. doi: 10.1007/s00404-012-2239-0.
To determine the efficacy and maternal complication rates of induction of labor, and to identify a concrete point in time for induction with the lowest possible risk for adverse events.
We designed a retrospective data analysis of all births at the general hospital of Vienna from 2003 to 2008(n = 16,872) and compared maternal complications of induced labors from 38 or more weeks of gestation versus spontaneous deliveries. The ethical committee of the General Hospital of Vienna and the Medical University of Vienna monitored this study and provided approval.
Women who had induction between 38 and 42 weeks of gestation (n = 1,254) had a significant higher risk for the need of a secondary cesarean (15.2 vs. 8.6%;p\0.001) and a higher chance for abnormally adherent placentas (1.5 vs. 2.5%; p = 0.13). The amount of maternal blood loss was equal in both groups. Concerning the question when to induct labor, there was no significant difference of distribution of complications between induced labors at term and induction within the next 10 days.
This study suggests that induction is associated with a higher risk for secondary cesareans and abnormally adherent placentas. The exact time of induction seems to be irrelevant between expected date of delivery and the next 10 days.
确定引产的疗效和产妇并发症发生率,并确定引产风险最低的具体时间点。
我们设计了一项对 2003 年至 2008 年维也纳综合医院所有分娩的回顾性数据分析,并比较了 38 周以上足月引产与自发性分娩的产妇并发症。维也纳综合医院伦理委员会和维也纳医科大学监测了这项研究,并提供了批准。
在 38 至 42 孕周之间引产的妇女(n = 1,254)需要二次剖宫产的风险显著更高(15.2%比 8.6%;p\0.001),异常粘连胎盘的可能性更高(1.5%比 2.5%;p = 0.13)。两组产妇出血量相等。关于何时引产的问题,足月引产和接下来 10 天内引产的并发症分布没有显著差异。
本研究表明,引产与二次剖宫产和异常粘连胎盘的风险增加相关。在预计分娩日期和接下来的 10 天之间,引产的确切时间似乎并不重要。