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2 型糖尿病患者的嗓音特征。

Vocal characteristics in patients with type 2 diabetes mellitus.

机构信息

Department of Otolaryngology, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Eur Arch Otorhinolaryngol. 2012 May;269(5):1489-95. doi: 10.1007/s00405-012-1933-7.

Abstract

The objective of this study is to report the vocal characteristics of patients with type 2 diabetes mellitus in relation to disease duration, glycemic control, and neuropathy. This is a prospective study. The setting is institutional setting. A total of 82 patients were recruited for this study, and a healthy control group matched according to age and gender was recruited. Subjects underwent acoustic analysis and perceptual evaluation using the GRABS classification where G stands for grading, R for roughness, A for asthenia, B for breathiness, and S for straining using a scale of 0–3 where o stands for normal and three for severe deviation from normal. There was no significant difference in any of the acoustic variables between diabetic patients and control. There was no significant difference in the mean score of any of the perceptual evaluation parameters between diabetic patients and control, despite the fact that the mean scores were all higher in the diseased group except for roughness. When looking at subgroups, we see that diabetic patients with poor glycemic control and with neuropathy had significantly higher mean score for the G overall grade of the voice compared to controls with P values of 0.005 and 0.009, respectively. What is also worth noting is that diabetic patients with poor glycemic control had more straining compared to controls, P value 0.043. Patients with type 2 diabetes mellitus and poor glycemic control or neuropathy have a significant difference in the grade of their voice compared to controls.

摘要

本研究旨在报告 2 型糖尿病患者的嗓音特征与疾病持续时间、血糖控制和神经病变的关系。这是一项前瞻性研究。研究地点为机构设置。本研究共招募了 82 名患者,并根据年龄和性别匹配了一个健康对照组。研究对象接受了声学分析和感知评估,使用 GRABS 分类法,其中 G 代表分级,R 代表粗糙度,A 代表乏力,B 代表气息声,S 代表紧张度,评分范围为 0-3,其中 0 表示正常,3 表示严重偏离正常。糖尿病患者与对照组在任何声学变量方面均无显著差异。尽管在患病组中,除了粗糙度之外,所有感知评估参数的平均评分都较高,但糖尿病患者与对照组之间的任何感知评估参数的平均评分均无显著差异。在亚组分析中,我们发现血糖控制不佳和有神经病变的糖尿病患者的嗓音总体 G 级评分明显高于对照组,P 值分别为 0.005 和 0.009。值得注意的是,血糖控制不佳的糖尿病患者与对照组相比,紧张度更高,P 值为 0.043。与对照组相比,血糖控制不佳或有神经病变的 2 型糖尿病患者的嗓音分级有显著差异。

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