University of Minnesota Medical Center, Department of Radiology, Center for Magnetic Resonance Research, Minneapolis, MN, USA.
NMR Biomed. 2012 Oct;25(10):1202-8. doi: 10.1002/nbm.2779. Epub 2012 Feb 7.
The objective of this study was to demonstrate the feasibility of simultaneous bilateral hip imaging at 7 Tesla. Hip joint MRI becomes clinically critical since recent advances have made hip arthroscopy an efficacious approach to treat a variety of early hip diseases. The success of these treatments requires a reliable and accurate diagnosis of intraarticular abnormalities at an early stage. Articular cartilage assessment is especially important to guide surgical decisions but is difficult to achieve with current MR methods. Because of gains in tissue contrast and spatial resolution reported at ultra high magnetic fields, there are strong expectations that imaging the hip joint at 7 Tesla will improve diagnostic accuracy. Furthermore, there is growing evidence that the majority of these hip abnormalities occur bilaterally, emphasizing the need for bilateral imaging. However, obtaining high quality images in the human torso, in particular of both hips simultaneously, must overcome a major challenge arising from the damped traveling wave behaviour of RF waves at 7 Tesla that leads to severe inhomogeneities in transmit B1 (B(1) (+) ) phase and magnitude, typically resulting in areas of low signal and contrast, and consequently impairing use for clinical applications. To overcome this problem, a 16-channel stripline transceiver RF coil was used, together with a B1 shimming algorithm aiming at maximizing B(1) (+) in six regions of interest over the hips that were identified on axial scout images. Our successful results demonstrate that this approach effectively reduces inhomogeneities observed before B1 shimming and provides high joint tissue contrast in both hips while reducing the required RF power. Critical to this success was a fast small flip angle B(1) (+) calibration scan that permitted the computation of subject-specific B1 shimming solutions, a necessary step to account for large spatial variations in B(1) (+) phase observed in different subjects.
本研究旨在展示在 7 特斯拉下同时进行双侧髋关节成像的可行性。髋关节 MRI 变得至关重要,因为最近的进展使髋关节镜检查成为治疗各种早期髋关节疾病的有效方法。这些治疗的成功需要在早期可靠且准确地诊断关节内异常。关节软骨评估对于指导手术决策尤为重要,但目前的磁共振方法很难实现。由于超高磁场下报告的组织对比度和空间分辨率的提高,人们强烈期望在 7 特斯拉下对髋关节进行成像将提高诊断准确性。此外,越来越多的证据表明,这些髋关节异常大多数是双侧发生的,强调了双侧成像的必要性。然而,在人体躯干中获得高质量的图像,特别是同时获得双侧髋关节的图像,必须克服在 7 特斯拉下 RF 波的阻尼行波行为引起的主要挑战,这会导致发射 B1(B(1) (+))相位和幅度的严重不均匀性,通常会导致低信号和对比度区域,从而影响临床应用。为了解决这个问题,使用了 16 通道 stripline 收发器射频线圈,以及旨在最大化髋关节六个感兴趣区域的 B(1) (+)的 B1 调谐算法,这些区域是在轴向 scout 图像上识别的。我们的成功结果表明,这种方法有效地减少了 B1 调谐前观察到的不均匀性,并在减少所需射频功率的同时为两个髋关节提供了高的关节组织对比度。这项成功的关键是快速小翻转角 B(1) (+)校准扫描,它允许计算特定于受试者的 B1 调谐解决方案,这是考虑到不同受试者中观察到的 B(1) (+)相位的大空间变化的必要步骤。