Surgical Services, Pain Management, Children's Hospital Central California, Madera, California 93636-8761, USA.
Pain Med. 2012 Mar;13(3):472-83. doi: 10.1111/j.1526-4637.2011.01324.x. Epub 2012 Feb 7.
The purpose of this study, in a sample of preschool children (ages 3-5 years; N = 47), was to evaluate the feasibility of scheduled analgesic dosing following outpatient tonsillectomy in order to optimize pain management.
Parents were instructed to give their child acetaminophen with hydrocodone (167 mg/5 mL) every 4 hours around the clock for the first 3 days following surgery. Parents recorded ratings of their child's pain with/without swallowing using the Faces, Legs, Activity, Cry, and Consolability (FLACC) behavioral pain scale, pain relief ratings, and severity of analgesic side effects in a home diary. Audiotaped interviews were conducted with parents to document descriptions of their experiences in managing their child's pain at home.
Mean FLACC scores with/without swallowing were less than two at each measurement time and pain relief scores increased over time. Total analgesic dose decreased, and the number of missed doses increased over the first 3 days after surgery. Moderate-to-severe daytime sedation, nausea, vomiting, and constipation were reported by parents.
Study results suggest that acetaminophen with hydrocodone is effective in relieving preschool children's pain following tonsillectomy and that parental adherence to a scheduled analgesic regimen decreases over time. Time-contingent dosing was associated with moderate to severe side effects and should be addressed in discharge teaching with parents. Findings provide insight into parents' perspective of pain management at home following tonsillectomy and methods for relieving their child's pain.
本研究旨在评估门诊扁桃体切除术后定时给予镇痛剂的可行性,以优化疼痛管理,研究对象为(3-5 岁)学龄前儿童(N=47)。
指导父母在手术后的前 3 天,每 4 小时给孩子服用对乙酰氨基酚氢可酮(167mg/5mL)。父母使用面部表情、腿部活动、哭泣、可安慰性(FLACC)行为疼痛量表记录孩子在吞咽和不吞咽时的疼痛评分、疼痛缓解评分和镇痛副作用的严重程度,并在家中日记中记录。对父母进行录音访谈,记录他们在家中管理孩子疼痛的经历。
每次测量时,FLACC 评分(有/无吞咽)均小于 2,疼痛缓解评分随时间增加而增加。总镇痛剂量减少,术后第 3 天漏服次数增加。父母报告了中度至重度日间镇静、恶心、呕吐和便秘。
研究结果表明,对乙酰氨基酚氢可酮可有效缓解学龄前儿童扁桃体切除术后的疼痛,且父母对定时镇痛方案的依从性随时间推移而降低。时间依赖性给药与中度至重度副作用相关,应在与父母的出院教育中予以解决。研究结果提供了父母对扁桃体切除术后家庭疼痛管理的看法以及缓解孩子疼痛的方法。