临床量表对半定量显性肝性脑病的评估及作用。

Assessment and usefulness of clinical scales for semiquantification of overt hepatic encephalopathy.

机构信息

Department of Psychiatry, University of California, San Diego, 220 Dickinson Street, Suite B (MC: 8231), San Diego, CA 92103, USA.

出版信息

Clin Liver Dis. 2012 Feb;16(1):27-42. doi: 10.1016/j.cld.2011.12.005.

DOI:10.1016/j.cld.2011.12.005

PMID:22321463

Abstract

Hepatic encephalopathy (HE) represents the effects of liver dysfunction on the brain. When HE is clinically obvious (eg, confusion, poor judgment, personality change), it is termed overt HE. The severity of HE is measured by different methods. Assessing the severity of HE is important for determining patient prognosis and effectiveness of therapy. This article discusses the different methods for grading HE, including clinical rating scales, neuropsychological tests, and neurophysiologic measures.

摘要

肝性脑病（HE）代表肝脏功能障碍对大脑的影响。当 HE 在临床上明显（例如，意识模糊、判断力差、性格改变）时，称为显性 HE。HE 的严重程度可以通过不同的方法来测量。评估 HE 的严重程度对于确定患者的预后和治疗效果非常重要。本文讨论了分级 HE 的不同方法，包括临床评分量表、神经心理学测试和神经生理学测量。