Shchukina V N, Loginova S Ia, Borisevich S V, Bondarev V P
Antibiot Khimioter. 2011;56(7-8):42-6.
Foreign experience with empirical management of severe acute respiratory syndrome (SARS) due to coronavirus, genotype IV is described. It is indicated that the data on the efficacy of ribavirin with respect to SARS in the patients are contradictory. The efficacy of two chemotherapeutics, i. e. lopinavir and ritonavir used in the SARS foci is confirmed. The drugs are at present applicable all over the world in retrovirus therapy of HIV infected subjects. The search for efficient Russian unspecific medicines for control of SARS is actual.
描述了国外对由冠状病毒IV型引起的严重急性呼吸综合征(SARS)进行经验性治疗的情况。结果表明,关于利巴韦林对SARS患者疗效的数据相互矛盾。已证实两种化疗药物,即洛匹那韦和利托那韦在SARS疫情地区使用的有效性。目前这两种药物在全球范围内用于HIV感染患者的逆转录病毒治疗。寻找有效的俄罗斯非特异性药物来控制SARS具有现实意义。