布氏锥虫鞭毛钙结合蛋白calflagin Tb24的(1)H、(15)N和(13)C化学位移归属
(1)H, (15)N, and (13)C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
作者信息
Xu Xianzhong, Olson Cheryl L, Engman David M, Ames James B
机构信息
Department of Chemistry, University of California, Davis, CA 95616, USA.
出版信息
Biomol NMR Assign. 2013 Apr;7(1):9-12. doi: 10.1007/s12104-012-9366-1. Epub 2012 Mar 2.
Abstract
Flagellar calcium binding proteins are expressed in a variety of trypanosomes and are potential drug targets for Chagas disease and African sleeping sickness. We report complete NMR chemical shift assignments of the flagellar calcium binding protein calflagin Tb24 of Trypanosoma brucei. (BMRB no. 18011).
摘要
鞭毛钙结合蛋白在多种锥虫中表达，是治疗恰加斯病和非洲昏睡病的潜在药物靶点。我们报告了布氏锥虫鞭毛钙结合蛋白calflagin Tb24的完整核磁共振化学位移归属（生物磁共振银行编号18011）。
相似文献
1
(1)H, (15)N, and (13)C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
Biomol NMR Assign. 2013 Apr;7(1):9-12. doi: 10.1007/s12104-012-9366-1. Epub 2012 Mar 2.
2
NMR structure of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
Protein Sci. 2012 Dec;21(12):1942-7. doi: 10.1002/pro.2167. Epub 2012 Oct 26.
3
Characterization of Calflagin, a Flagellar Calcium-Binding Protein from Trypanosoma congolense.
PLoS Negl Trop Dis. 2016 Apr 7;10(4):e0004510. doi: 10.1371/journal.pntd.0004510. eCollection 2016 Apr.
4
Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane.
J Cell Sci. 2009 Mar 15;122(Pt 6):867-74. doi: 10.1242/jcs.041764. Epub 2009 Feb 24.
5
The gene family of EF-hand calcium-binding proteins from the flagellum of Trypanosoma brucei.
Biochem J. 1994 Dec 15;304 ( Pt 3)(Pt 3):833-41. doi: 10.1042/bj3040833.
6
The predominant calcimedins from Trypanosoma brucei comprise a family of flagellar EF-hand calcium-binding proteins.
Biochem J. 1992 Oct 1;287 ( Pt 1)(Pt 1):187-93. doi: 10.1042/bj2870187.
7
Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infection.
Eukaryot Cell. 2010 Jun;9(6):934-42. doi: 10.1128/EC.00086-10. Epub 2010 Apr 23.
8
Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella.
J Cell Sci. 2007 Feb 1;120(Pt 3):478-91. doi: 10.1242/jcs.03352. Epub 2007 Jan 16.
9
H, C and N resonance assignments of NEDD8 from Trypanosoma brucei.
Biomol NMR Assign. 2018 Apr;12(1):159-161. doi: 10.1007/s12104-018-9800-0. Epub 2018 Jan 11.
10
H, C and N resonance assignments of TbBDF5-bromo1 domain from Trypanosoma brucei.
Biomol NMR Assign. 2022 Oct;16(2):253-255. doi: 10.1007/s12104-022-10088-1. Epub 2022 Jun 2.
引用本文的文献
1
Calcium-dependent membrane association of a flagellar calcium sensor does not require calcium binding.
Mol Biochem Parasitol. 2015 May;201(1):72-75. doi: 10.1016/j.molbiopara.2015.06.003. Epub 2015 Jun 19.
2
Exploiting image registration for automated resonance assignment in NMR.
J Biomol NMR. 2015 Jun;62(2):143-56. doi: 10.1007/s10858-015-9926-7. Epub 2015 Apr 1.
3
NMR structure of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
Protein Sci. 2012 Dec;21(12):1942-7. doi: 10.1002/pro.2167. Epub 2012 Oct 26.
本文引用的文献
1
Molecular determinants of ciliary membrane localization of Trypanosoma cruzi flagellar calcium-binding protein.
J Biol Chem. 2011 Sep 23;286(38):33109-17. doi: 10.1074/jbc.M111.240895. Epub 2011 Jul 22.
2
Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infection.
Eukaryot Cell. 2010 Jun;9(6):934-42. doi: 10.1128/EC.00086-10. Epub 2010 Apr 23.
3
Flagellar membrane localization via association with lipid rafts.
J Cell Sci. 2009 Mar 15;122(Pt 6):859-66. doi: 10.1242/jcs.037721. Epub 2009 Feb 24.
4
Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane.
J Cell Sci. 2009 Mar 15;122(Pt 6):867-74. doi: 10.1242/jcs.041764. Epub 2009 Feb 24.
5
Structural insights into membrane targeting by the flagellar calcium-binding protein (FCaBP), a myristoylated and palmitoylated calcium sensor in Trypanosoma cruzi.
J Biol Chem. 2008 Aug 22;283(34):23388-96. doi: 10.1074/jbc.M803178200. Epub 2008 Jun 17.
6
A flagellum-specific calcium sensor.
J Biol Chem. 2005 Dec 2;280(48):40104-11. doi: 10.1074/jbc.M505777200. Epub 2005 Sep 7.
7
The neuronal calcium-sensor proteins.
Biochim Biophys Acta. 2004 Dec 6;1742(1-3):59-68. doi: 10.1016/j.bbamcr.2004.08.008.
8
Structural characterization of a recombinant flagellar calcium-binding protein from Trypanosoma cruzi.
Biochim Biophys Acta. 2003 Dec 1;1652(2):107-14. doi: 10.1016/j.bbapap.2003.08.008.
9
Identification of calcium binding sites in the trypanosome flagellar calcium-acyl switch protein.
Mol Biochem Parasitol. 1999 Jun 25;101(1-2):61-70. doi: 10.1016/s0166-6851(99)00055-9.
10
Flagellar protein localization mediated by a calcium-myristoyl/palmitoyl switch mechanism.
EMBO J. 1999 Apr 15;18(8):2057-65. doi: 10.1093/emboj/18.8.2057.
Zotero 插件