Hong Sung Noh, Yang Dong-Hoon, Kim Young-Ho, Hong Sung Pil, Shin Sung Jae, Kim Seong-Eun, Lee Bo In, Lee Suck-Ho, Park Dong Il, Kim Hyun-Soo, Yang Suk-Kyun, Kim Hyo Jong, Kim Se Hyung, Kim Hyun Jung
Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2012 Feb;59(2):99-117. doi: 10.4166/kjg.2012.59.2.99.
Post-polypectomy surveillance has become a major indication for colonoscopy as a result of increased use of screening colonoscopy in Korea. However, because the medical resource is limited, and the first screening colonoscopy produces the greatest effect on reducing the incidence and mortality of colorectal cancer, there is a need to increase the efficiency of postpolypectomy surveillance. In the present report, a careful analytic approach was used to address all available evidences to delineate the predictors for advanced neoplasia at surveillance colonoscopy. Based on the results of review of the evidences, we elucidated the high risk findings of the index colonoscopy as follows: 1) 3 or more adenomas, 2) any adenoma larger than 10 mm, 3) any tubulovillous or villous adenoma, 4) any adenoma with high-grade dysplasia, and 5) any serrated polyps larger than 10 mm. In patients without any high-risk findings at the index colonoscopy, surveillance colonoscopy should be performed five years after index colonoscopy. In patients with one or more high risk findings, surveillance colonoscopy should be performed three years after polypectomy. However, the surveillance interval can be shortened considering the quality of the index colonoscopy, the completeness of polyp removal, the patient's general condition, and family and medical history. This practical guideline cannot totally take the place of clinical judgments made by practitioners and should be revised and supplemented in the future as new evidence becomes available.
由于韩国结肠镜筛查的使用增加,息肉切除术后监测已成为结肠镜检查的主要指征。然而,由于医疗资源有限,且首次结肠镜筛查对降低结直肠癌的发病率和死亡率效果最佳,因此有必要提高息肉切除术后监测的效率。在本报告中,我们采用了严谨的分析方法来梳理所有现有证据,以确定监测结肠镜检查时高级别瘤变的预测因素。基于证据回顾结果,我们明确了初次结肠镜检查的高风险发现如下:1)3个或更多腺瘤;2)任何直径大于10毫米的腺瘤;3)任何管状绒毛状或绒毛状腺瘤;4)任何伴有高级别异型增生的腺瘤;5)任何直径大于10毫米的锯齿状息肉。在初次结肠镜检查时无任何高风险发现的患者中,应在初次结肠镜检查后5年进行监测结肠镜检查。在有一项或多项高风险发现的患者中,应在息肉切除术后3年进行监测结肠镜检查。然而,考虑到初次结肠镜检查的质量、息肉切除的完整性、患者的一般状况以及家族史和病史,监测间隔可以缩短。本实用指南不能完全取代从业者的临床判断,未来应随着新证据的出现进行修订和补充。