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白檀木七味蜜膏对白化大鼠的免疫调节活性

Immunomodulatory activity of Vachadhatryadi Avaleha in albino rats.

作者信息

Rajagopala S, Ashok B K, Ravishankar B

机构信息

Assistant Professor, Department of Kaumarabhritya, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.

出版信息

Ayu. 2011 Apr;32(2):275-8. doi: 10.4103/0974-8520.92546.

Abstract

The present study is carried out to evaluate the immuno-modulatory activity of Vacha Dhatryadi Avaleha in albino rats. Vacha Dhatryadi Avaleha was prepared by classical method and evaluated for humoral antibody formation and cell-medicated immunity in established experimental models. Test formulation was administered at the dose of 900 mg/kg and parameters like hemagglutination titer, ponderal changes, histopathology of immunological organs and immunological paw edema were recorded. Vacha Dhatryadi Avaleha significantly enhanced antibody formation and moderately suppressed the immunological edema. The present study concludes that Vachadhatryadi Avaleha has immunopotentiating activity.

摘要

本研究旨在评估瓦查达特里阿迪阿瓦莱哈(Vacha Dhatryadi Avaleha)对白化病大鼠的免疫调节活性。瓦查达特里阿迪阿瓦莱哈采用经典方法制备,并在已建立的实验模型中评估其对体液抗体形成和细胞介导免疫的作用。将受试制剂以900毫克/千克的剂量给药,并记录诸如血凝滴度、体重变化、免疫器官的组织病理学以及免疫性爪肿胀等参数。瓦查达特里阿迪阿瓦莱哈显著增强了抗体形成,并适度抑制了免疫性肿胀。本研究得出结论,瓦查达特里阿迪阿瓦莱哈具有免疫增强活性。

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