圣约翰草对炎症的抑制作用：一种常见草药被忽视的潜力。

Inhibitory effects of St. John's Wort on inflammation: ignored potential of a popular herb.

作者信息

Olajide Olumayokun A

机构信息

Regulatory Affairs Department, Holland and Barrett UK Ltd, Nuneaton, Warwickshire, UK.

出版信息

J Diet Suppl. 2009;6(1):28-32. doi: 10.1080/19390210802687247.

DOI:10.1080/19390210802687247

PMID:22435352

Abstract

St. John's wort (Hypericum perforatum L., family Hypericaceae) is a flowering herb, which has been used traditionally for decades in Europe and other parts of the world for the treatment of depressive mood disorders. A number of clinical trials support its application in the treatment of depressive mood symptoms. Although not commonly known for this use, St John's wort is also reputed for its usefulness in inflammatory conditions such as sciatica and fibromyalgia. This article discusses evidence from in vitro and in vivo studies supporting a possible use of St. John's wort as an anti-inflammatory remedy, in addition to its well-known antidepressant effects.

摘要

圣约翰草（贯叶连翘，金丝桃科）是一种开花草本植物，在欧洲和世界其他地区，它作为治疗抑郁情绪障碍的药物已有数十年的传统应用历史。多项临床试验支持其在治疗抑郁情绪症状方面的应用。尽管圣约翰草的这种用途并不广为人知，但它在坐骨神经痛和纤维肌痛等炎症性疾病中的效用也颇负盛名。本文除了讨论圣约翰草广为人知的抗抑郁作用外，还探讨了体外和体内研究的证据，以支持其作为抗炎药物的潜在用途。