Dhasmana Satish, Singh Vibha, Pal U S
Department of Anesthesiology, Chattrapati Shahuji Maharaj Medical University, Lucknow, U.P., India.
Natl J Maxillofac Surg. 2010 Jul;1(2):112-6. doi: 10.4103/0975-5950.79211.
The purpose of this study was to evaluate the postoperative pain control and mouth opening in patients undergoing temporomandibular joint interpositional gap arthroplasty by either placing an epidural catheter in the incision wound and infusing ropivacaine 0.25% or by using a transdermal fentanyl patch.
The study was prospective, randomized and double blind. Eighty patients belonging to American Society of Anesthesiologists grade I and II, 18-32 years of age, scheduled for temporomandibular joint interpositional gap arthroplasty were randomized into 2 groups; ropivacaine group (G rop): to receive 0.25% ropivacaine infusion and transdermal fentanyl group (G tf): to receive transdermal fentanyl patch. For postoperative pain (Visual Analog Score [VAS]) and analgesic requirements were assessed 2, 4 and 8 h after surgery and each morning, until and 4 days after surgery.
Time to first analgesic requirement was found to be significantly (P < 0.0001) higher in G rop (49 ± 6.7) as compared with G tf (32 ± 9.1) VAS were also significantly lower in G rop throughout the postoperative period. Postoperatively, mouth opening was better in G rop as compared with G tf, which was statistically significant.
It was concluded that by placing an epidural catheter at the incision wound and continuously infusing with ropivacaine 0.25% effectively controls the postoperative pain in patients undergoing temporomandibular joint interpositional gap arthroplasty and provides better postoperative mouth opening.
本研究旨在评估颞下颌关节间隙植入性关节成形术患者术后的疼痛控制情况及开口度,方法是在切口处放置硬膜外导管并输注0.25%的罗哌卡因,或使用透皮芬太尼贴剂。
本研究为前瞻性、随机、双盲研究。将80例年龄在18 - 32岁、美国麻醉医师协会分级为I级和II级、计划行颞下颌关节间隙植入性关节成形术的患者随机分为两组;罗哌卡因组(Grop):接受0.25%罗哌卡因输注;透皮芬太尼组(Gtf):接受透皮芬太尼贴剂。术后2、4、8小时及术后每天早晨直至术后4天评估术后疼痛(视觉模拟评分[VAS])和镇痛需求。
发现Grop组首次需要镇痛的时间(49±6.7)明显高于Gtf组(32±9.1)(P<0.0001)。在整个术后期间,Grop组的VAS也明显更低。术后,Grop组的开口度比Gtf组更好,具有统计学意义。
得出结论,在切口处放置硬膜外导管并持续输注0.25%的罗哌卡因可有效控制颞下颌关节间隙植入性关节成形术患者的术后疼痛,并使术后开口度更好。