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一名患有迷走神经刺激器的癫痫儿童因渐进性导线牵引导致难治性发作性心动过缓:一种迟发性并发症。

Intractable episodic bradycardia resulting from progressive lead traction in an epileptic child with a vagus nerve stimulator: a delayed complication.

作者信息

Clark Aaron J, Kuperman Rachel A, Auguste Kurtis I, Sun Peter P

机构信息

Department of Neurological Surgery, University of California, San Francisco, CA, USA.

出版信息

J Neurosurg Pediatr. 2012 Apr;9(4):389-93. doi: 10.3171/2011.12.PEDS11124.

Abstract

Vagus nerve stimulation (VNS) is used as palliation for adult and pediatric patients with intractable epilepsy who are not candidates for curative resection. Although the treatment is generally safe, complications can occur intraoperatively, perioperatively, and in a delayed time frame. In the literature, there are 2 reports of pediatric patients with implanted VNS units who had refractory bradycardia that resolved after the stimulation was turned off. The authors report the case of a 13-year-old boy with a history of vagus nerve stimulator placement at 2 years of age, who developed intractable episodic bradycardia that persisted despite the cessation of VNS and whose imaging results suggested vagus nerve tethering by the leads. He was subsequently taken to the operating room for exploration, where it was confirmed that the stimulator lead was exerting traction on the vagus nerve, which was displaced from the carotid sheath. After the vagus nerve was untethered and the leads were replaced, the bradycardia eventually resolved with continual effective VNS therapy. When placing a VNS unit in a very young child, accommodations must be made for years of expected growth. Delayed intractable bradycardia can result from a vagus nerve under traction by tethered stimulator leads.

摘要

迷走神经刺激术(VNS)用于治疗无法进行根治性切除的难治性癫痫的成人和儿童患者。尽管该治疗总体安全,但并发症可发生在术中、围手术期以及延迟期。文献中有2例植入VNS装置的儿科患者出现难治性心动过缓,在刺激关闭后缓解的报道。作者报告了1例13岁男孩的病例,该男孩在2岁时植入了迷走神经刺激器,出现了难治性发作性心动过缓,尽管VNS已停止,但仍持续存在,其影像学结果提示迷走神经被导线束缚。随后他被送往手术室进行探查,术中证实刺激器导线对迷走神经施加了牵引力,导致迷走神经从颈动脉鞘移位。在解除迷走神经束缚并更换导线后,通过持续有效的VNS治疗,心动过缓最终得以缓解。在非常年幼的儿童中植入VNS装置时,必须考虑到多年的预期生长。由束缚的刺激器导线牵引迷走神经可导致延迟性难治性心动过缓。

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