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[刚果民主共和国东部唇腭裂的流行病学研究方法]

[The epidemiological approach of clefts lip and palate in the eastern of Democratic Republic of Congo].

作者信息

Longombe A O, Tshimbila Kabangu J M V

机构信息

Université de Kisangani, Doctors On Call for Service Medical Center, Goma, République Démocratique du Congo.

出版信息

Ann Chir Plast Esthet. 2012 Jun;57(3):245-9. doi: 10.1016/j.anplas.2012.02.012. Epub 2012 Mar 31.

Abstract

OBJECTIVE

This study aims to present the epidemiological profile of clefts lip/palate observed in the eastern of Democratic Republic of Congo (DRC) from January 2002 to May 2004, period of civil wars.

METHOD

It is a retrospective study realized at Doctors on Call for service Learning Center (DOCS LC) in Goma/DRC concerning 89 cases of cleft lip/palate operated during the same period. The data processing was facilitated by the software package SPSS 17.0 installed in the IT center of DOCS.

RESULTS

The average age of the consultation is 9.9 years with extreme of zero and 42 years. Both sexes are concerned: 50.6% of male and 49.4% of female. The more cleft extends from the superior lip to the palate through the alveolus, the more the frequency of the various types of clefts lips/palate decreases: 59.6% (simple clefts lip), 37.1% (labio-alveolar clefts), and 2.2% (cleft palate). The left incomplete cleft lip variety represents 33.7% of all varieties. Most of clefts lips/palate come from the first to the fifth pregnancy with a peak of frequency (19.1%) in the second pregnancy. No family history about congenital deformation was found from 97% of our patients.

CONCLUSION

The epidemiology of cleft lip/palate in our area would be more connected to environmental factors than genetics: no family history of congenital deformation was seen for most of our patients during this period of civil war.

摘要

目的

本研究旨在呈现2002年1月至2004年5月刚果民主共和国(DRC)东部内战期间观察到的唇腭裂流行病学概况。

方法

这是一项在刚果民主共和国戈马的随叫随到医生服务学习中心(DOCS LC)进行的回顾性研究,涉及同期接受唇腭裂手术的89例病例。数据处理借助安装在DOCS信息技术中心的SPSS 17.0软件包得以便利进行。

结果

就诊的平均年龄为9.9岁,年龄范围从0岁至42岁。男女均有涉及:男性占50.6%,女性占49.4%。唇腭裂越从唇上部延伸至腭部并经过牙槽,各类唇腭裂的发生率越低:单纯唇裂占59.6%,唇牙槽裂占37.1%,腭裂占2.2%。左侧不完全唇裂类型占所有类型的33.7%。大多数唇腭裂发生在第一胎至第五胎,第二胎时发生率最高(19.1%)。97%的患者未发现先天性畸形的家族史。

结论

我们地区唇腭裂的流行病学情况与环境因素的关联可能大于与遗传因素的关联:在这段内战期间,我们的大多数患者未发现先天性畸形的家族史。

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