脓毒症中的心肌功能障碍：一个巨大的、尚未解决的难题。
Myocardial dysfunction in sepsis: a large, unsolved puzzle.
作者信息
Fernandes Constantino Jose, de Assuncao Murillo Santucci Cesar
机构信息
Hospital Israelita Albert Einstein, Avenida Albert Einstein 627/701, 05661-901 Morumbi, SP, Brazil.
出版信息
Crit Care Res Pract. 2012;2012:896430. doi: 10.1155/2012/896430. Epub 2012 Mar 13.
Abstract
Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac dysfunction. Biomarkers to detect cardiac depression have been used to recognize developing problems, but the actual impact of these tools remains unclear.
摘要
脓毒症在全球范围内具有较高的发病率和死亡率。脓毒症期间心脏抑制在心肌功能障碍中的作用仍有待阐明。本综述试图总结我们对心脏功能障碍背后的解剖学、组织病理学和病理生理学机制的理解。用于检测心脏抑制的生物标志物已被用于识别正在出现的问题，但这些工具的实际影响仍不明确。
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