一项关于次氯酸钠与甲醛甲酚牙髓切断术治疗乳磨牙的随机研究。

A randomized study of sodium hypochlorite versus formocresol pulpotomy in primary molar teeth.

机构信息

Department of Pediatric Dentistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

出版信息

Int J Paediatr Dent. 2013 Mar;23(2):145-52. doi: 10.1111/j.1365-263X.2012.01237.x. Epub 2012 Apr 13.

DOI:10.1111/j.1365-263X.2012.01237.x

PMID:22502601

Abstract

BACKGROUND

Alternatives to vital pulpotomy treatment in primary teeth are being sought because of the high formaldehyde content of traditional formocresol (FC) pulpotomy medicaments.

AIM

The aim was to compare the clinical and radiographic success of vital pulpotomy treatment in primary molars using 3% sodium hypochlorite (NaOCl) versus a 1:5 dilution of Buckley's FC.

DESIGN

Pulpotomies were performed in primary molars of healthy children between 3 and 10 years old. Sixty-five primary teeth were randomized into two groups that were evaluated for treatment outcomes. Following treatment, the pulp chamber was filled with zinc oxide eugenol (ZnOE) and restored with a stainless steel crown cemented with glass ionomer cement. Clinical and radiographic outcomes were recorded at 6 and 12 months.

RESULTS

The control (FC) and experimental (NaOCl) groups demonstrated 100% clinical success at 6 and 12 months. The NaOCl group had 86% (19/22) radiographic success at 6 months and 80% (12/15) at 12 months. The FC group had 84% (21/25) radiographic success at 6 months and 90% (9/10) at 12 months. No significant differences were found in the radiographic outcomes between the two groups at 6 and 12 months (Fisher's exact test; P=0.574 and P=0.468, respectively).

CONCLUSION

NaOCl demonstrated clinical and radiographic success comparable to FC.

摘要

背景

由于传统甲醛甲酚（FC）牙髓切断药物中甲醛含量高，人们正在寻找替代恒牙活髓切断治疗的方法。

目的

本研究旨在比较 3%次氯酸钠（NaOCl）与 Buckley 的 FC 1:5 稀释液用于恒前磨牙活髓切断治疗的临床和放射学成功率。

设计

在 3 至 10 岁健康儿童的恒磨牙中进行牙髓切断术。将 65 颗恒磨牙随机分为两组，评估治疗结果。治疗后，用氧化锌丁香酚（ZnOE）填充牙髓腔，并用玻璃离子水门汀粘结不锈钢冠修复。分别在 6 个月和 12 个月记录临床和放射学结果。

结果

对照组（FC）和实验组（NaOCl）在 6 个月和 12 个月时的临床成功率均为 100%。NaOCl 组在 6 个月时的放射成功率为 86%（19/22），在 12 个月时为 80%（12/15）。FC 组在 6 个月时的放射成功率为 84%（21/25），在 12 个月时为 90%（9/10）。两组在 6 个月和 12 个月时的放射学结果无显著差异（Fisher 确切检验；P=0.574 和 P=0.468）。