Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
J Womens Health (Larchmt). 2012 Jul;21(7):776-82. doi: 10.1089/jwh.2011.3224. Epub 2012 Apr 16.
To examine time intervals from cervical cancer screening to diagnosis and treatment initiation among low-income and uninsured women in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) during two consecutive time periods.
We analyzed NBCCEDP data for women with abnormal Pap tests (n=100,167), from which 1,417 invasive cervical cancers were diagnosed. We examined two time intervals for this study: diagnostic interval (time from abnormal Pap test to the date of definitive diagnosis) and treatment initiation interval (time from definitive diagnosis to treatment initiation) for two time periods: 1996-2002 and 2003-2009. We compared median time intervals for diagnostic and treatment initiation using the Kruskal-Wallis test. Adjusted proportions (predicted marginals) were calculated using logistic regression to examine diagnosis and treatment within program benchmarks (≤60 days).
Median diagnostic intervals decreased overall by 6 days (54 vs. 48 days, p<0.001). This decrease in the median diagnostic interval was noted for all variables examined. The median treatment initiation intervals remained stable over the two time periods.
Women screened by the NBCCEDP receive diagnostic follow-up and initiate treatment within preestablished program guidelines.
在两个连续时期内,检查国家乳房和子宫颈癌早期检测计划(NBCCEDP)中低收入和没有保险的妇女从子宫颈癌筛查到诊断和治疗开始的时间间隔。
我们分析了 NBCCEDP 数据,其中包括 100,167 例异常巴氏试验的妇女,其中诊断出 1,417 例浸润性宫颈癌。我们研究了两个时间间隔:诊断间隔(从异常巴氏试验到确诊日期的时间)和治疗开始间隔(从确诊到治疗开始的时间),分为两个时期:1996-2002 年和 2003-2009 年。我们使用 Kruskal-Wallis 检验比较了诊断和治疗开始的中位数时间间隔。使用逻辑回归计算调整后的比例(预测边际),以检查方案基准(≤60 天)内的诊断和治疗。
总体而言,中位诊断间隔缩短了 6 天(54 天对 48 天,p<0.001)。所有检查的变量都观察到中位诊断间隔缩短。两个时期的中位治疗开始间隔保持稳定。
接受 NBCCEDP 筛查的妇女在既定方案准则内接受诊断随访并开始治疗。