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尼日利亚南南地区一家三级医疗机构的献血者血液采集与输血传播病毒感染风险

Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria.

作者信息

Nwogoh Benedict, Ikpomwen O D, Isoa E M

机构信息

Department of Hematology and Blood Transfusion, University of Benin Teaching Hospital, Benin City, Nigeria.

出版信息

Niger Med J. 2011 Oct;52(4):227-9. doi: 10.4103/0300-1652.93793.

Abstract

BACKGROUND

Blood and blood products are scarce commodities. The demand often outweighs the supply. This study is directed at investigating the blood procurement sources and the risk of viral transfusion transmissible infection.

MATERIALS AND METHODS

The records of the blood transfusion unit of a tertiary health facility in south-south Nigeria were studied. The procurement and screening records from 1 January to 31 December 2009 were analyzed.

RESULTS

7,552 donor records were analyzed, 6,931 were commercial donor and 621 replacement donors. 891 commercial donors were infected, 500 (7.2%) were HIV positive, 323 (4.7%) HBV positive, 42 (0.6%) had HIV and HBV co-infection, while 28 (0.4%) were HCV positive. Twenty-three replacement donors were infected, 16 (2.6%) were HIV positive, 6 (1%) were HBV positive, while 1 (0.2%) were HCV positive. None of the replacement donors had co-infection. The risk of infection was significantly higher with commercial donor procurement (X2=45.07, P<0.001, OD=3.845).

CONCLUSION

Commercial blood donors are still the major source of blood to the hospital and they also have the highest prevalence of transfusion transmissible viral infections in this region thus constitute a major risk transmitting infections to potential recipients.

摘要

背景

血液及血液制品是稀缺资源。需求常常超过供应。本研究旨在调查血液采集来源及病毒输血传播感染的风险。

材料与方法

对尼日利亚西南部一家三级医疗机构输血科的记录进行研究。分析了2009年1月1日至12月31日的采集及筛查记录。

结果

共分析了7552份献血者记录,其中6931份为商业献血者,621份为替代献血者。891名商业献血者感染,500名(7.2%)HIV阳性,323名(4.7%)HBV阳性,42名(0.6%)HIV和HBV合并感染,28名(0.4%)HCV阳性。23名替代献血者感染,16名(2.6%)HIV阳性,6名(1%)HBV阳性,1名(0.2%)HCV阳性。替代献血者均无合并感染。商业献血者采集的感染风险显著更高(X2=45.07,P<0.001,OD=3.845)。

结论

商业献血者仍是该医院血液的主要来源,且在该地区输血传播病毒感染的患病率最高,因此构成了将感染传播给潜在受血者的主要风险。

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