Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
J Surg Oncol. 2013 Jan;107(1):86-96. doi: 10.1002/jso.23137. Epub 2012 Apr 24.
Local failure remains a major issue for patients with both resectable and locally advanced pancreatic cancer. The role of radiation therapy in the management of this disease is less clear and represents an area of some controversy. The objective of this review is to present the rationale for radiation therapy in pancreatic cancer, as well as to discuss the potential limitations and caveats of the currently available studies.
局部失败仍然是可切除和局部晚期胰腺癌患者的主要问题。放射治疗在这种疾病的治疗中的作用不太明确,这也是一个存在争议的领域。本文的目的是介绍放射治疗在胰腺癌中的应用原理,并讨论目前可用研究的潜在局限性和注意事项。