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成人胆总管囊肿腹腔镜整块完整切除的早期经验

Early experience of laparoscopic complete en bloc excision for choledochal cysts in adults.

机构信息

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736, Korea.

出版信息

Surg Endosc. 2012 Nov;26(11):3324-9. doi: 10.1007/s00464-012-2299-z. Epub 2012 May 2.

Abstract

BACKGROUND

For choledochal cyst, the treatment of choice is total excision of the cyst because there is a risk of biliary cancer including the gallbladder. The current report describes the authors' early experiences using their technique of laparoscopic en bloc excision of choledochal cysts with Roux-en-Y biliary reconstruction.

METHODS

Between September 2009 and July 2011, laparoscopic excision for choledochal cyst was attempted for 20 patients at the Division of Hepatobiliary and Pancreatic Surgery, Asan Medical Center. Clinical, radiologic, and surgical data were analyzed retrospectively.

RESULTS

The mean age of the patients was 37.8 ± 11.1 years (range, 18-65 years), and the male-to-female ratio was 1:4.0 (4:16). According to Todani's classification, there were four type 1a cases, seven type 1c cases, and nine type 4a cases. The mean operation time was 395.8 ± 58.7 min. No perioperative transfusions were required. The average body mass index was 23.5 ± 4.04 kg/m(2). Conversion to laparotomy was required for seven patients (35 %) due to bleeding (n = 1), Roux loop venous congestion (n = 1), abdominal obesity (n = 2), and severe fibrosis and inflammation around the cyst (n = 3). No malignancies were identified. Of the 13 patients who underwent laparoscopy, the jejunojejunostomy was created extracorporeally for the first 2 patients and intracorporeally for the subsequent 11 patients. All hepaticojejunostomies were performed intracorporeally. Oral feeding was resumed on postoperative day 3. The mean postoperative hospital stay was 9.3 days (range, 8-36 days). No major complications or mortalities occurred.

CONCLUSIONS

The morbidity and mortality rates for the authors' method are comparable with previously reported results. Although the conversion rate, mean operation time, and hospital stay were greater than reported in some studies, this probably reflected the authors' learning curve for this technically challenging procedure. They believe laparoscopic approaches will eventually become an advantageous treatment option for laparotomy offered to selected choledochal cyst patients.

摘要

背景

对于胆总管囊肿,由于存在包括胆囊在内的胆管癌风险,治疗的首选方法是囊肿全切除。本报告描述了作者采用腹腔镜整块切除胆总管囊肿并进行 Roux-en-Y 胆道重建技术的早期经验。

方法

2009 年 9 月至 2011 年 7 月期间,峨山医学中心肝胆胰外科对 20 例患者尝试进行腹腔镜胆总管囊肿切除术。对临床、影像学和手术数据进行回顾性分析。

结果

患者的平均年龄为 37.8±11.1 岁(范围 18 - 65 岁),男女比例为 1:4.0(4:16)。根据 Todani 分类,有 4 例 1a 型、7 例 1c 型和 9 例 4a 型。平均手术时间为 395.8±58.7 分钟。围手术期无需输血。平均体重指数为 23.5±4.04kg/m²。7 例患者(35%)因出血(n = 1)、Roux 袢静脉淤血(n = 1)、腹部肥胖(n = 2)以及囊肿周围严重纤维化和炎症(n = 3)而需要转为开腹手术。未发现恶性肿瘤。在 13 例接受腹腔镜手术的患者中,前 2 例患者的空肠吻合术在体外进行,随后 11 例患者在体内进行。所有肝空肠吻合术均在体内进行。术后第 3 天恢复经口进食。术后平均住院时间为 9.3 天(范围 8 - 36 天)。未发生重大并发症或死亡。

结论

作者方法的发病率和死亡率与先前报道的结果相当。尽管中转率、平均手术时间和住院时间比一些研究报道的要长,但这可能反映了作者在这项技术要求高的手术中的学习曲线。他们认为,腹腔镜手术最终将成为为选定的胆总管囊肿患者提供的开腹手术的一种优势治疗选择。

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