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亚健康状态中医证型诊断分析:结构方程模型方法。

Diagnosis Analysis of 4 TCM Patterns in Suboptimal Health Status: A Structural Equation Modelling Approach.

机构信息

School of Preclinical Medicine, Beijing University of Chinese Medicine, No. 11, Beisanhuan Donglu, Chaoyang District, Beijing 100029, China.

出版信息

Evid Based Complement Alternat Med. 2012;2012:970985. doi: 10.1155/2012/970985. Epub 2012 Apr 10.

Abstract

Background. We illustrated an example of structure equation modelling (SEM) in the research on SHS to explore the diagnosis of the Sub optimal health status (SHS) and provide evidence for the standardization of traditional Chinese medicine (TCM) patterns in SHS. And the diagnosis of 4 TCM patterns in SHS was evaluated in this analysis. Methods. This study assessed data on 2807 adults (aged 18 to 49) with SHS from 6 clinical centres. SEM was used to analyze the patterns of SHS in TCM. Parameters in the introduced model were estimated by the maximum likelihood method. Results. The discussed model fits the SHS data well with CFI = 0.851 and RMSEA = 0.075. The direct effect of Qi deficiency pattern on dampness pattern had the highest magnitude (value of estimate is 0.822). With regard to the construct of "Qi deficiency pattern", "fire pattern", "stagnation pattern" and "dampness pattern", the indicators with the highest load were myasthenia of limbs, vexation, deprementia, and dizziness, respectively. It had been shown that estimate factor should indicate the important degree of different symptoms in pattern. Conclusions. The weights of symptoms in the respective pattern can be statistical significant and theoretical meaningful for the 4 TCM patterns identification in SHS research. The study contributed to a theoretical framework, which has implications for the diagnosis points of SHS.

摘要

背景。我们在 SHS 研究中展示了结构方程模型(SEM)的一个实例,以探索亚健康状态(SHS)的诊断,并为 SHS 中医模式的标准化提供证据。并在本分析中评估了 SHS 中 4 种中医模式的诊断。

方法。本研究评估了来自 6 个临床中心的 2807 名成年人(18 至 49 岁)的 SHS 数据。采用 SEM 分析中医 SHS 的模式。引入模型中的参数采用极大似然法估计。

结果。所讨论的模型与 CFI = 0.851 和 RMSEA = 0.075 很好地拟合了 SHS 数据。气亏模式对湿邪模式的直接影响最大(估计值为 0.822)。关于“气亏模式”、“火邪模式”、“郁结模式”和“湿邪模式”的结构,肢体无力、烦躁、健忘和头晕等指标的负荷最高。结果表明,估计因子应该表明模式中不同症状的重要程度。

结论。对于 SHS 研究中的 4 种中医模式识别,各模式中症状的权重具有统计学意义和理论意义。该研究为 SHS 的诊断要点提供了理论框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2d/3329144/44ea5fe0cd6d/ECAM2012-970985.001.jpg

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