非典型息肉样腺肌瘤进展为子宫内膜样腺癌。
Atypical polypoid adenomyomas progressed to endometrial endometrioid adenocarcinomas.
机构信息
Department of Pathology, Beijing Fuxing Hospital affiliated to the Capital University of Medical Sciences, Beijing Fuxing Menwai Street #20, Beijing, 100038, China.
出版信息
Arch Gynecol Obstet. 2012 Sep;286(3):707-10. doi: 10.1007/s00404-012-2355-x. Epub 2012 May 4.
INTRODUCTION
Atypical polypoid adenomyoma (APA) is an uncommon uterine tumor which is composed of atypical endometrial glands and cellular smooth-muscle stroma. At present APA is categorized as a benign lesion and treated conservatively in the literatures. However, there are also several cases reported that progressed to endometrial endometrioid adenocarcinoma (EEC) till now. Here, we present two more rare cases of APA that may have undergone progression to EEC.
MATERIALS
Two patients who had APA 6 and 4 years ago, respectively, and had ECC were reported.
METHODS
The history of the two patients and the literatures were retrospectively reviewed.
CONCLUSIONS
The truth that APA may have a chance to progress to carcinoma suggests that APA is at least an indicator lesion for the development of EEC, and highlights that clinicians should carefully monitor the patients, and a meticulous follow-up examination is mandatory.
简介
非典型息肉样腺肌瘤（APA）是一种不常见的子宫肿瘤，由非典型子宫内膜腺体和细胞平滑肌基质组成。目前，APA 在文献中被归类为良性病变并进行保守治疗。然而，也有几例报道称其进展为子宫内膜内异样腺癌（EEC）。在此，我们报告了另外两例可能进展为 EEC 的罕见 APA 病例。
材料
两名患者分别在 6 年前和 4 年前患有 APA，并患有 ECC。
方法
回顾性分析了两名患者的病史和文献。
结论
APA 有进展为癌的可能，这表明 APA 至少是 EEC 发展的一个指标性病变，这强调了临床医生应仔细监测患者，必须进行细致的随访检查。
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