Rodionov A N, Samtsov A V
Vestn Dermatol Venerol. 1990(7):68-71.
A female patient suffering from the ulcerative form of skin sarcoidosis is described and the literature dealing with this problem is reviewed. Peculiar features of this case are described: ulceration of the nodes, which is an extremely rare phenomenon; no involvement of other organs, lungs included, was detectable, which is not typical of ulcerative sarcoidosis; small-nodular elements are parallelled by nodes (Boeck's small-nodular sarcoid and Darier-Roussy's subcutaneous sarcoids) in this patient, this evidencing an uniform pathologic process in the skin and subcutaneous fat. Ulceration in this patient is explained by the development of allergic vasculitis of the immediate hypersensitivity type (leukocytoclastic vasculitis and manifest increase of the level of circulating immune complexes). Prednisolone therapy has resulted in an excellent clinical effect.
本文描述了一名患有溃疡性皮肤结节病的女性患者,并对有关该问题的文献进行了综述。描述了该病例的特殊特征:结节溃疡,这是一种极为罕见的现象;未检测到其他器官受累,包括肺部,这在溃疡性结节病中并不典型;在该患者中,小结节成分与结节(伯克氏小结节性结节病和达里埃 - 鲁西皮下结节病)并存,这证明皮肤和皮下脂肪存在统一的病理过程。该患者的溃疡是由速发型超敏反应性过敏性血管炎(白细胞破碎性血管炎和循环免疫复合物水平明显升高)的发展所解释的。泼尼松龙治疗产生了极佳的临床效果。