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经肛门内镜微创手术:肥胖患者中直肠中段病变的安全治疗方法。

Transanal endoscopic microsurgery: safe for midrectal lesions in morbidly obese patients.

机构信息

Section of Colon and Rectal Surgery, Washington Hospital Center, 106 Irving St. NW, Suite 2100N, Washington, DC 20020-2975, USA.

出版信息

Am J Surg. 2012 Sep;204(3):402-5. doi: 10.1016/j.amjsurg.2011.11.011. Epub 2012 May 11.

Abstract

BACKGROUND

Transanal endoscopic microsurgery is a safe option for proximal rectal tumors in morbidly obese patients for whom transabdominal pelvic dissection often is fraught with morbidity.

METHODS

From a database of 318 patients who underwent transanal endoscopic microsurgery, we report a retrospective case-control study of 9 patients with a body mass index range of 35 to 66 with sessile rectal lesions 6 to 15 cm from the anal verge who underwent transanal endoscopic microsurgery. Case subjects were compared with 15 controls and matched for age, tumor type, and level of tumor. The average body mass index of controls was 30 (P < .001). By using t test analysis, perioperative outcomes (surgical time, blood loss, and hospital length of stay) and postoperative complications were compared.

RESULTS

Sessile tumors were located 7 to 11 cm from the anal verge with a diameter of 1 to 4 cm. Patient and tumor factors such as age, distal tumor margin from anal verge, and tumor diameter were not significantly different between case subjects and controls. Surgical blood loss, surgical time, and hospital length of stay were not significantly different between the 2 groups. One complication occurred among the cases. No complications occurred in the control group. All patients had complete surgical resections with negative margins.

CONCLUSIONS

Transanal endoscopic microsurgery in morbidly obese patients is a safe, feasible, and a viable alternative to low anterior resection.

摘要

背景

经肛门内镜微创手术是病态肥胖患者直肠近端肿瘤的安全选择,因为对这些患者进行经腹盆腔解剖往往会带来较高的发病率。

方法

我们从接受经肛门内镜微创手术的 318 例患者的数据库中报告了一项回顾性病例对照研究,该研究纳入了 9 例 BMI 范围在 35 至 66 之间、距肛门缘 6 至 15cm 处有直肠固有病变的患者,这些患者接受了经肛门内镜微创手术。病例组与 15 例对照组进行比较,并按年龄、肿瘤类型和肿瘤水平进行匹配。对照组的平均 BMI 为 30(P<0.001)。通过使用 t 检验分析,比较了围手术期结果(手术时间、失血量和住院时间)和术后并发症。

结果

固有肿瘤位于距肛门缘 7 至 11cm 处,直径为 1 至 4cm。病例组和对照组之间的患者和肿瘤因素(如年龄、距肛门缘的远端肿瘤边缘和肿瘤直径)无显著差异。两组的手术失血量、手术时间和住院时间无显著差异。病例组发生 1 例并发症。对照组无并发症发生。所有患者均行完全性手术切除,切缘均为阴性。

结论

经肛门内镜微创手术在病态肥胖患者中是一种安全、可行的选择,可替代低位前切除术。

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