Grupo de Pesquisa em Saúde Materna e Infantil, Núcleo de Pesquisa em Micronutrientes, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Public Health Nutr. 2012 Oct;15(10):1802-9. doi: 10.1017/S1368980012001206. Epub 2012 May 14.
To estimate the frequency of anaemia in pregnant women before and after the fortification of flours with Fe.
Retrospective study developed from secondary data obtained from medical records.
Two health units in Rio de Janeiro, Brazil.
Socio-economic, demographic, obstetric and Hb concentration data were collected of 778 pregnant women attending prenatal care. Two study groups were created: the first referred to the period before fortification (G1, n 391), including women whose parturition happened before June 2004; and the second referred to the period after fortification (G2, n 387), including women whose last menstrual cycle happened after June 2005. The Hb cut-off point adopted for anaemia diagnosis was <11.0 g/dl.
In linear regression models, when Hb concentration was expressed as a dependent variable, women in G2 presented Hb concentration 0.26 g/dl and 0.36 g/dl higher during the second and third trimesters of pregnancy, respectively, compared with G1. In logistic regression models where the dependent variable was anaemia during the second and third trimesters, it was verified that being a member of G2 was a protective factor against anaemia in the third trimester. Regarding the presence of anaemia at any gestational moment, it was verified that being a member of G2 represented a protective factor against anaemia during pregnancy.
Results indicate the protective effect of the fortification of flours with Fe in the fight against gestational anaemia, contributing to prevention and control of this nutritional disorder among pregnant women.
评估铁强化面粉强化前后孕妇贫血的频率。
从病历中获得的二手数据进行的回顾性研究。
巴西里约热内卢的两个卫生单位。
收集了 778 名接受产前保健的孕妇的社会经济、人口统计学、产科和血红蛋白浓度数据。创建了两个研究组:第一组是强化前时期(G1,n=391),包括分娩发生在 2004 年 6 月之前的妇女;第二组是强化后时期(G2,n=387),包括末次月经周期发生在 2005 年 6 月之后的妇女。贫血诊断采用的血红蛋白截断值为<11.0 g/dl。
在线性回归模型中,当血红蛋白浓度作为因变量时,与 G1 相比,G2 组妇女在妊娠第二和第三期的血红蛋白浓度分别高 0.26 g/dl 和 0.36 g/dl。在第二和第三孕期贫血的二项逻辑回归模型中,证实 G2 组是第三孕期贫血的保护因素。关于任何妊娠时刻存在贫血,证实 G2 组是妊娠期间贫血的保护因素。
结果表明铁强化面粉强化具有防治妊娠期贫血的保护作用,有助于预防和控制孕妇的这种营养障碍。