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超重或肥胖患者接受微创与开放经椎间孔腰椎椎间融合术后的临床结果比较。

Comparison of the clinical outcome in overweight or obese patients after minimally invasive versus open transforaminal lumbar interbody fusion.

作者信息

Wang Jian, Zhou Yue, Feng Zhang Zheng, Qing Li Chang, Jie Zheng Wen, Liu Jie

机构信息

Department of Orthopaedic Surgery, Affiliated Xinqiao Hospital, The Third Military Medical University, Shapingba District, Chongqing, People's Republic of China.

出版信息

J Spinal Disord Tech. 2014 Jun;27(4):202-6. doi: 10.1097/BSD.0b013e31825d68ac.

Abstract

STUDY DESIGN

This is a prospective single-center nonrandomized control clinical study involving 81 overweight or obese patients who underwent minimally invasive or open transforaminal lumbar interbody fusion (TLIF).

OBJECTIVE

The objective of this study was to evaluate the safety and efficacy of minimally invasive TLIF as an alternative technique in overweight or obese patients.

SUMMARY OF BACKGROUND DATA

Spinal surgery in obese patients is associated with increased complications, blood loss, and operative times. The potential benefits of minimally invasive lumbar surgery in obese patients have been discussed in a few studies. However, there have been no prospective clinical reports published on the comparison of minimally invasive or open TLIF (OTLIF) in obese patients.

METHODS

Eighty-one patients, 25 male and 56 female, with an average age of 55.3 years (43-81 y) were prospectively evaluated. The main inclusion criterion was a body mass index ≥25. The mean body mass index was 28.9±3.2. All patients suffering from lumbar canal stenosis (n=43), spondylolisthesis (n=29), or postlaminectomy instability (n=9) underwent 1-level minimally invasive TLIF (MiTLIF, n=43) or OTLIF (n=39). The following data were compared between 2 groups: operative time, blood loss, x-ray exposure time, clinical and radiographic outcomes, and perioperative complications. The clinical outcome was assessed using the visual analogue scale and the Oswestry Disability Index (ODI). Radiographic evaluation of the lumbar spine was performed at 12 months postoperatively.

RESULTS

In comparison with the OTLIF group, the MiTLIF group had significantly less operating time, less blood loss, and less postoperative back pain. The radiation time was significantly longer in the MiTLIF group. The clinical outcomes (Oswestry Disability Index scores) were basically identical in the 2 groups. Radiographic evaluation showed satisfactory bony union at the fixed level in both the MiTLIF group (42/43 cases) and the OTLIF group (38/39 cases). Overall complication rates were slightly higher in the OTLIF group, with 17.9% of overweight or obese patients having perioperative complications.

CONCLUSIONS

MiTLIF is a safe and reliable procedure for treatment of overweight or obese patients. The minimally invasive technique offers several potential advantages when compared with the open procedure. Although this technique needs a longer x-ray exposure time, it may still be a good option for overweight or obese patients.

摘要

研究设计

这是一项前瞻性单中心非随机对照临床研究,纳入了81例接受微创或开放经椎间孔腰椎椎体间融合术(TLIF)的超重或肥胖患者。

目的

本研究旨在评估微创TLIF作为超重或肥胖患者替代技术的安全性和有效性。

背景数据总结

肥胖患者的脊柱手术与并发症增加、失血增多及手术时间延长相关。少数研究探讨了微创腰椎手术对肥胖患者的潜在益处。然而,尚无关于肥胖患者微创与开放TLIF(OTLIF)比较的前瞻性临床报告。

方法

前瞻性评估了81例患者,其中男性25例,女性56例,平均年龄55.3岁(43 - 81岁)。主要纳入标准为体重指数≥25。平均体重指数为28.9±3.2。所有患有腰椎管狭窄(n = 43)、椎体滑脱(n = 29)或椎板切除术后不稳(n = 9)的患者均接受了1节段微创TLIF(MiTLIF,n = 43)或OTLIF(n = 39)。比较了两组之间的以下数据:手术时间、失血量、X线暴露时间、临床和影像学结果以及围手术期并发症。使用视觉模拟量表和Oswestry功能障碍指数(ODI)评估临床结果。术后12个月对腰椎进行影像学评估。

结果

与OTLIF组相比,MiTLIF组手术时间明显更短、失血量更少且术后背痛更少。MiTLIF组的辐射时间明显更长。两组的临床结果(Oswestry功能障碍指数评分)基本相同。影像学评估显示MiTLIF组(42/43例)和OTLIF组(38/39例)固定节段均达到满意的骨融合。OTLIF组的总体并发症发生率略高,17.9%的超重或肥胖患者有围手术期并发症。

结论

MiTLIF是治疗超重或肥胖患者的一种安全可靠的手术方法。与开放手术相比,微创技术具有若干潜在优势。尽管该技术需要更长的X线暴露时间,但对于超重或肥胖患者仍可能是一个不错的选择。

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