Iwasaki Tomohiro, Yamamoto Takashi, Inoue Ken-ichiro, Takaku Ken-ichi
Department of Internal Medicine, Nanbugo General Hospital, Japan.
Intern Med. 2012;51(11):1419-23. doi: 10.2169/internalmedicine.51.7364. Epub 2012 Jun 1.
Lemierre's syndrome (LS) is characterized by pharyngitis followed by septicemia, internal jugular vein thrombophlebitis, and metastatic embolization in general. LS is commonly caused by Fusobacterium necrophorum. Herein, we present a case of LS with liver abscesses that presented as a sole metastatic lesion. We were not able to diagnose LS until Fusobacterium necrophorum was isolated due to the lack of the common involvement. Doripenem was effective against the pathologic features including the liver abscesses. LS should be taken into consideration when clinicians find liver abscesses following pharyngitis even when the common complications of LS are not detected.
勒米尔综合征(LS)的特征通常为咽炎后继发败血症、颈内静脉血栓性静脉炎和转移性栓塞。LS通常由坏死梭杆菌引起。在此,我们报告一例伴有肝脓肿的LS病例,该肝脓肿为唯一的转移病灶。由于缺乏常见受累表现,在分离出坏死梭杆菌之前我们未能诊断出LS。多利培南对包括肝脓肿在内的病理特征有效。当临床医生发现咽炎后出现肝脓肿时,即使未检测到LS的常见并发症,也应考虑到LS。